Recombinant Netrin 1 (Ntn1) Mus musculus (Mouse) Recombinant protein

NTN1L; Epididymis tissue protein Li 131P

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Cytoplasm
  • Molecular Mass 58.5kDa, Accurate 58kDa(Analysis of differences refer to the manual)
  • Residues & TagsPro313~Pro565 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point9.0
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  • Recombinant Netrin 1 (Ntn1) Packages (Simulation)
  • Recombinant Netrin 1 (Ntn1) Packages (Simulation)
  • Recombinant Netrin 1 (Ntn1) Figure . Gene Sequencing (extract)
  • RPB827Mu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Netrin-1: A Novel Universal Biomarker of Human Kidney InjuryPubMed: 20620466
  • Plasma netrin-1 is a diagnostic biomarker of human cancersPubMed: PMC3143477
  • Cord blood netrin-1 and -4 concentrations in term pregnancies with normal, restricted and increased fetal growthInformahealthcare: Source
  • Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesityPubmed:24584118
  • Cord blood netrin-1 and-4 concentrations in term pregnancies with normal, restricted and increased fetal growthPubmed:24716747
  • Urinary netrin-1 and KIM-1 as early biomarkers for septic acute kidney injuryPubmed:25154466
  • Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC)articles:10.1186
  • The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium.pubmed:29156815
  • Neuroprotection Exerted by Netrin-1 and Kinesin Motor KIF1A in Secondary Brain Injury following Experimental Intracerebral Hemorrhage in RatsPubmed:29375318
  • Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptorPubmed:29662125
  • Relationship of serum netrin-1 levels with breast massesDoi: 10.22391/fppc.467700
  • Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesityPubmed: 30910812
  • Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes MellitusPubmed: 30897795
  • Serum netrin-1 as a biomarker for colorectal cancer detectionPubmed: 32474463
  • Níveis Elevados de Netrina-1 e IL-1β em Mulheres Idosas com SCA: Pior Prognóstico no Acompanhamento de Dois Anos
  • Association of plasma netrin-1 level with inflammatory balance and comorbidities in patients with acute exacerbation of COPD33853303
  • Conductive Hydrogel Conduits with Growth Factor Gradients for Peripheral Nerve Repair in Diabetics with Non‐suture TapePubmed:35670309

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