Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) Homo sapiens (Human) Recombinant protein

CD265; TNFRSF11A; TNFRSF11-A; ODFR; OFE; TRANCER; Osteoclast differentiation factor receptor; Tumor Necrosis Factor Receptor Superfamily,Member 11a,NFKB Activator

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 33.9kDa, Accurate 44kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal330~Lys615 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point4.8
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  • Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) Packages (Simulation)
  • Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) Packages (Simulation)
  • Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) Figure. Gene Sequencing (Extract)
  • RPC057Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Human polymorphonuclear neutrophils express the receptor activator of NFκB (RANK) and are activated by its ligand RANKLWiley: source
  • Valvular osteoclasts in calcification and aortic valve stenosis severityPubMed: 23452891
  • Receptor Activator of Nuclear Transcription Factor NF-κB(RANK), Its Ligand RANKL, and Natural Inhibitor of RANKL Osteoprotegerin (OPG) in the Blood Serum of Patients with Primary Bone TumorsDOI:110.1007/s10517-017-3832-9
  • IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathwayPubmed: 32347300

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