Recombinant Angiopoietin Like Protein 8 (ANGPTL8) Mus musculus (Mouse) Recombinant protein

RIFL; TD26; C19orf80; Lipasin; Betatrophin; Hepatocellular Carcinoma-Associated Protein TD26

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 24.2kDa, Accurate 24kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal16~Ala198 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point7.3
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  • Recombinant Angiopoietin Like Protein 8 (ANGPTL8) Packages (Simulation)
  • Recombinant Angiopoietin Like Protein 8 (ANGPTL8) Packages (Simulation)
  • RPW803Mu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Increased Maternal and Cord Blood Betatrophin in Gestational DiabetesPubMed: 26115519
  • Serum betatrophin level increased in subjects with metabolic syndrome: a case-control studywp-content:10563
  • Serum betatrophin level increased in subjects with nonalcoholic fatty liver diseasefiles:ijcem0020951.pdf
  • Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversypubmed:27410263
  • Relationship between serum betatrophin levels and the first-phase of glucose-stimulated insulin secretionpubmed:27554132
  • Aumento del nivel de betatrofina en suero en sujetos con síndrome metabólico: estudio de casos y controles:
  • Levels of betatrophin decrease during pregnancy despite increased insulin resistance, beta-cellfunction and triglyceride levels.pubmed:27555469
  • Decreased circulating levels of betatrophin in Chinese women with polycystic ovary syndrome:
  • Serum concentrations of betatrophin and its association with indirect indices of insulin resistance and beta cell function in women with polycystic ovary …pubmed:28702052
  • Angiopoietin-like protein 8: an attractive biomarker for the evaluation of subjects with insulin resistance and related disorderspubmed:28965028
  • ANGPTL8 (Betatrophin) Role in Diabetes and Metabolic Diseasespubmed:28722798
  • The Correlation Between Circulating Betatrophin and Insulin Resistance in General Population: A Meta-Analysispubmed:28931172
  • ANGPTL8: an important regulator in metabolic disordersPubmed:29719529
  • ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different MannersPubmed: 30405056
  • Angptl8 mediates food-driven resetting of hepatic circadian clock in micePubmed: 31388006
  • The Impact of Psoriasis and Metabolic Syndrome on the Systemic Inflammation and Oxidative Damage to Nucleic AcidsPubmed: 32537470
  • Genetic and Metabolic Determinants of Plasma Levels of ANGPTL833619548
  • Association of betatrophin amounts with 25-(OH) D levels in patients with gestational diabetes mellitus33879746
  • Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet?¡­34035808

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