Recombinant Complement Factor B (CFB) Rhesus monkey (Simian) Recombinant protein

CF-B; BF; BFD; CFAB; GBG; H2-Bf; PBF2; B-Factor; Properdin; Properdin factor B; C3/C5 convertase; Glycine-rich beta glycoprotein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 44.2kDa, Accurate 34&44kDa(Analysis of differences refer to the manual)
  • Residues & TagsGly35~Asn160 with N-terminal His and GST Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 80%
  • Isoelectric Point8.2
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  • Recombinant Complement Factor B (CFB) Packages (Simulation)
  • Recombinant Complement Factor B (CFB) Packages (Simulation)
  • RPC011Si01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Complement in patients receiving maintenance hemodialysis: functional screening and quantitative analysisBioMed: 14712369
  • Identification and Confirmation of Differentially Expressed Fucosylated Glycoproteins in the Serum of Ovarian Cancer Patients Using a Lectin Array and LC–MS/MSACS: pr300330z
  • Atypical hemolytic uremic syndrome: Korean pediatric seriesPubMed: 25443527
  • Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitisPubmed:27235358
  • Adipose tissue complement factor B promotes adipocyte maturation.pubmed:29137982
  • Serum exosomes from newborn piglets restrict porcine epidemic diarrhea virus infection
  • Identification of susceptibility locus shared by IgA nephropathy and inflammatory bowel disease in a Chinese Han populationPubmed: 31857673
  • Association between thrombotic microangiopathy and activated alternative complement pathway in malignant nephrosclerosis33367879
  • Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse33410734
  • Early Diagnostic Ability of Human Complement Factor B in Pancreatic Cancer Is Partly Linked to Its Potential Tumor-Promoting Role34766501
  • A Three-Protein Panel to Support the Diagnosis of Sepsis in ChildrenPubmed:35329889

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