Recombinant Chitinase-3-like Protein 1 (CHI3L1) Rattus norvegicus (Rat) Recombinant protein

GP39; CHI3-L1; YKL40; Chondrex; Chitinase 3-Like 1; Chondrocyte Protein YKL40; 39 kDa synovial protein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus, Cytoplasm, Extracellular matrix
  • Molecular Mass 31.2kDa, Accurate 29kDa(Analysis of differences refer to the manual)
  • Residues & TagsTyr117~Lys364 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point8.7
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  • Recombinant Chitinase-3-like Protein 1 (CHI3L1) Packages (Simulation)
  • Recombinant Chitinase-3-like Protein 1 (CHI3L1) Packages (Simulation)
  • RPB463Ra01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Serum YKL-40: a potential biomarker for psoriasis or endothelial dysfunction in psoriasis?Pubmed:25421412
  • YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatmentPubmed:25578181
  • Assessment of pulsed electromagnetic field therapy with Serum YKL‐40 and ultrasonography in patients with knee osteoarthritisPubMed: 25955771
  • YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodelingPubmed:27013031
  • Compositions and Methods for Diagnosing Lung Cancery2016:0077095.html
  • Chronic obstructive pulmonary disease (COPD)--from biomarkers to clinical phenotypesISBN:978-951-51-4039-5
  • YKL-40 is a local marker for inflammation in patients with pseudoexfoliation syndromePubmed: 30560917
  • Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of Chi3l1 expressionPubmed: 31002152
  • Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic PatientsPubmed: 31717649
  • Oligodendrocyte Progenitor Cells Increase Chi3l1 Secretion in Exosome to Activate Myh9 and Promote Proliferation through Connexin47 Connected to …
  • High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease33814903

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