Recombinant Granzyme B (GZMB)

GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 188.00 US$ 470.00 US$ 940.00 US$ 2,820.00 US$ 7,050.00
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Overview

Properties

Product No.RPA600Po01
Organism SpeciesSus scrofa; Porcine (Pig) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategoryApoptosis Tumor immunity Infection immunity Immune molecule

Source Prokaryotic expression, Host E.coli
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationCytoplasm
Molecular Mass 29.2kDa, Accurate 29kDa(Analysis of differences refer to the manual)
Residues & TagsGly19~Leu246 with N-terminal His Tag
Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits Freeze-dried powder, Purity > 90%
Isoelectric Point10.2

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Packages (Simulation)
Packages (Simulation)

Figure . Gene Sequencing (extract)

Figure. SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70Pubmed:24691976
Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 MelanomaPubmed:24818259
Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopicdermatitis.pubmed:27686401
Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatmentPubmed:29983866
A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumorsPubmed: 31695790
Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma34377237