Recombinant Growth Differentiation Factor 11 (GDF11) Homo sapiens (Human) Recombinant protein

BMP11; Bone morphogenetic protein 11

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 16.2kDa, Accurate 16kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsn299~Ser407 with N-terminal His Tag
  • Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point7.7
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  • Recombinant Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Recombinant Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Recombinant Growth Differentiation Factor 11 (GDF11) Figure . Gene Sequencing (extract)
  • RPC113Hu02.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic micePubMed: 26317549
  • TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Micepubmed:27611336
  • GDF11 is increased in patients with myelodysplastic syndromefiles:ijcep0024948.pdf
  • GDF11 does not improve the palmitate induced insulin resistance in C2C12.pubmed:28485800
  • РОЛЬ ДИФФЕРЕНЦИРОВОЧНОГО ФАКТОРА РОСТА 11 (GDF11) В РЕГУЛЯЦИИ ЛИПИДНОГО ОБМЕНА И КАРДИОГЕМОДИНАМИЧЕСКИХ ФУНКЦИЙ …Cyberleninka:Source
  • GDF11 is increased in patients with aplastic anemiaPubmed: 30727851
  • GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs33764670
  • The relationship between transforming growth factor β superfamily members (GDF11 and BMP4) and lumbar spine bone mineral density in postmenopausal Chinese …34417839
  • Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and …34336096

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