Eukaryotic Hemojuvelin (HJV) Homo sapiens (Human) Eukaryotic protein

HFE2; HFE2A; HJV; JH; RGMC; hemochromatosis type 2(Juvenile); Haemojuvelin; RGM domain family member C

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1ug (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 66.1kDa, Accurate 66kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln36~Asp400 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point7.7
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  • Eukaryotic Hemojuvelin (HJV) Packages (Simulation)
  • Eukaryotic Hemojuvelin (HJV) Packages (Simulation)
  • Eukaryotic Hemojuvelin (HJV) Gene sequencing
  • EPB995Hu61.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in PBS or others.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Effect of Iron Overload and Iron Deficiency on Liver Hemojuvelin ProteinPubMed: PMC3356351
  • Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary ReportPubMed: 25881778
  • Soluble hemojuvelin in transfused and untransfused thalassaemic subjectsdoi:10.1111
  • The secret war against counterfeit sciencepubmed:28492262
  • Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgeryPubmed:29699579
  • Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac SurgeryPubmed:29386545
  • The functional role of hemojuvelin in acute ischemic strokePubmed: 31307288
  • Oxidative damage and iron dyshomeostasis in thalassemic patients
  • Caffeine and alcohol-friends or foes of human iron stores?Pubmed:35063815
  • Urinary Biomarkers Can Predict Weaning From Acute Dialysis Therapy in Critically Ill PatientsPubmed:35311928
  • The Relationships among Plasma Fetuin-B, Thyroid Autoimmunity, and Fertilization Rate In Vitro Fertilization and Embryo TransferPubmed:35340679

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