Recombinant High Temperature Requirement Factor A1 (HTRA1) 
HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1
Overview
Properties
- Product No.RPL604Co02
- Organism SpeciesEscherichia coli Same name, Different species.
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Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only - DownloadInstruction Manual
- CategoryEnzyme & Kinase
- Source Prokaryotic expression, Host E.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane
- Molecular Mass 15.5kDa, Accurate 16kDa(Analysis of differences refer to the manual)
- Residues & TagsLys304~Lys442 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
- Traits Freeze-dried powder, Purity > 97%
- Isoelectric Point9.9
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Packages (Simulation)
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Packages (Simulation)
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SDS-PAGE
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ISO9001: 2008, ISO13485: 2003 Registered
Sequence
Usage
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
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Endotoxin Removal Kit
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Recombinant Protein Customized Service
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Buffer
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Endotoxin Removal Kit II
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
Citations
- Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGRPubMed: 23083999
- Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsiaPubMed: 22964307
- Association of frailty with the serine protease HtrA1 in older adultsPubmed:27058767
- HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathwaysfiles:ijcep0069706.pdf
- Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?
- HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathwayPubmed: 31497227
- First trimester HtrA1 maternal plasma level and spontaneous preterm birthPubmed: 32102578
- Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population33743591