Eukaryotic Interleukin 1 Receptor Antagonist (IL1RA) Homo sapiens (Human) Eukaryotic protein

IL1RN; IL1-RA; ICIL1RA; IL1ra3; IL1F3; IRAP;IL-1RA; Interleukin-1 Family Member 3; IL1 inhibitor; Anakinra

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1ug (determined by the LAL method)
  • Subcellular LocationSecreted, Cytoplasm
  • Molecular Mass 18.7kDa, Accurate 22/25/27kDa(Analysis of differences refer to the manual)
  • Residues & TagsArg26~Glu177 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point5.4
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  • Eukaryotic Interleukin 1 Receptor Antagonist (IL1RA) Packages (Simulation)
  • Eukaryotic Interleukin 1 Receptor Antagonist (IL1RA) Packages (Simulation)
  • Eukaryotic Interleukin 1 Receptor Antagonist (IL1RA) Gene sequencing
  • EPA223Hu61.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in PBS or others.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Mucosal imbalance of interleukin-1β and interleukin-1 receptor antagonist in canine inflammatory bowel diseaseScienceDirect: S1090023312000962
  • Daily quercetin supplementation over a period of two weeks results in a moderate accumulation of total plasma flavonols in horsesResearchgate:Source
  • Synovial Fluid and Serum Concentrations of Interleukin-1 Receptor Antagonist and Interleukin-1Science: Article
  • A Two-Week Quercetin Supplementation in Horses Results in Moderate Accumulation of Plasma Flavonol ConcentrationsScience: Article
  • Evidence-based review of efficacy and adverse effects of joint medication and evaluation of synovial fluid and serum markers for osteoarthritis in the horsereceive:101658
  • Interleukin 1 receptor antagonist and 2′-5′-oligoadenylate synthetase-like molecules as novel biomarkers for multiple sclerosis patients in Bahrainpubmed:29141788
  • A similar pro/anti-inflammatory cytokine balance is present in the airways of competitive athletes and non-exercising asthmaticspubmed:28822267
  • Winter ambient training conditions are associated with increased bronchial hyperreactivity and with shifts in serum innate immunity proteins in young …Pubmed:29379533
  • Effect of interleukin‐1β on occludin mRNA expression in the duodenal and colonic mucosa of dogs with inflammatory bowel diseasePubmed:29572935
  • M10, a Myricetin-3-ObD-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in MicePubmed: 33041798

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