Recombinant Interleukin 1 Zeta (IL1z) Homo sapiens (Human) Recombinant protein

IL1F7; IL37; FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H4; IL-1RP1; IL1H4; IL1RP1; Interleukin 37; Interleukin-1-Related Protein; Interleukin 1 Family, Member 7

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 23.1kDa, Accurate 23kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal46~Asp218 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point8.9
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  • Recombinant Interleukin 1 Zeta (IL1z) Packages (Simulation)
  • Recombinant Interleukin 1 Zeta (IL1z) Packages (Simulation)
  • RPE842Hu02.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Levels of interleukin-37 in gingival crevicular fluid, saliva, or plasma in periodontal diseasePubmed:25399716
  • Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout.pubmed:27863506
  • IL‐37 inhibits invasion and metastasis in non‐small cell lung cancer by suppressing the IL‐6/STAT3 signaling pathwayPubmed:29575809

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