Recombinant Orexin A (OXA) Mus musculus (Mouse) Recombinant protein

Hypocretin-1

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular Locationn/a
  • Molecular Mass n/a, Accurate n/a(Analysis of differences refer to the manual)
  • Residues & Tags
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Pointn/a
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  • Recombinant Orexin A (OXA) Packages (Simulation)
  • Recombinant Orexin A (OXA) Packages (Simulation)
  • RPA607Mu01.png SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in PBS or others.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Neuro-Glial and Systemic Mechanisms of Pathological Responses in Rat Models of Primary Blast Overpressure Compared to “Composite” BlastPubMed: PMC3275793
  • Pentylenetetrazol-induced seizures are exacerbated by sleep deprivation through orexin receptor-mediated hippocampal cell proliferationPubmed: 23852314
  • Orexin-A-induced ERK1/2 activation reverses impaired spatial learning and memory in pentylenetetrazol-kindled rats via OX1R-mediated hippocampal neurogenesis.Pubmed: 24321199
  • Orexin in Patients with Alcohol Dependence Treated for Relapse Prevention: A Pilot StudyPubMed: 26597795
  • Evaluation of Antidiabetic And Insulintropic Potential of Nigella Sativa Seeds Water Extract and /or Alpha Lipoic Acid in Type 2 Diabetic RatsIssues%20Pdf: Vol.2
  • Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished ChildrenPubMed: 26831553
  • Resuscitation therapy for traumatic brain injury-induced coma in rats: mechanisms of median nerve electrical stimulationPubMed: 26170820
  • Wake-promoting actions of median nerve stimulation in TBI-induced coma: An investigation of orexin-A and orexin receptor 1 in the hypothalamic regionPubMed: 26059340
  • Application of the Co-culture Membrane System Pointed to a Protective Role of Catestatin on Hippocampal Plus Hypothalamic Neurons Exposed to Oxygen and Glucose Deprivationarticle:10.1007
  • Wake-promoting effects of vagus nerve stimulation after traumatic brain injury: upregulation of orexin-A and orexin receptor type 1 expression in the prefrontal …Pubmed:29557373
  • Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in menPubmed: 31426866
  • Relationship Between Orexin-A and Insulin Resistance in Patients with Type 2 Diabetes Mellitus
  • Changes in the Orexin System in Rats Exhibiting Learned Helplessness Behaviors34942932

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