Recombinant Programmed Cell Death Protein 1 (PD1)     
     
CD279; PDCD1; SLEB2; HPD1P
Overview
Properties
- Product No.RPA751Ra01
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- 
                                Applications
                                Positive Control; Immunogen; SDS-PAGE; WB.
 If bio-activity of the protein is needed, please check active protein.
 Research use only
- DownloadInstruction Manual
- CategoryApoptosisImmune moleculeEndocrinologyAutoimmunity
- Source Prokaryotic expression, Host E.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane
- Molecular Mass 55.0kDa, Accurate 55kDa(Analysis of differences refer to the manual)
- Residues & TagsPro39~Ser266 with N-terminal His and GST Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder, Purity > 95%
- Isoelectric Point6.0
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            Sequence
 
                                        
                                    Usage
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
- 
                 Endotoxin Removal Kit Endotoxin Removal Kit
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                 BCA Protein Quantification Kit BCA Protein Quantification Kit
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                 Protein Labeling Customized Service Protein Labeling Customized Service
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                 Molecular Mass Marker for Protein Molecular Mass Marker for Protein
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                 Recombinant Protein Customized Service Recombinant Protein Customized Service
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                 Monoclonal Antibody Customized Service Monoclonal Antibody Customized Service
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                 Polyclonal Antibody Customized Service Polyclonal Antibody Customized Service
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                 Protein Activity Test Experiment Service Protein Activity Test Experiment Service
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                 Immunoprecipitation (IP) Experiment Service Immunoprecipitation (IP) Experiment Service
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                 Buffer Buffer
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                 Endotoxin Removal Kit II Endotoxin Removal Kit II
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                 Real Time PCR Experimental Service Real Time PCR Experimental Service
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                 Spike RBD Protein (S-RBD) Spike RBD Protein (S-RBD)
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                 Protein G Protein G
- 
                 Protein A Protein A
Citations
- Circulating soluble programmed death-1 levels may differentiate immune-tolerant phase from other phases and hepatocellular carcinoma from other clinical diseases in chronic hepatitis B virus infection.pubmed:28545019
- Потенциальные биомаркеры эффективности терапии ниволумабом при метастатическом почечно-клеточном раке:
- АНАЛИЗ РЕЗУЛЬТАТОВ ЛЕЧЕНИЯ БОЛЬНЫХ МЕТАСТАТИЧЕСКИМ РАКОМ ПОЧКИ, ПОЛУЧАВШИХ АНТИ-PD-1‑ТЕРАПИЮ В РАМКАХ ПРОГРАММЫ …
- Design and Synthesis of A PD-1 Binding Peptide and Evaluation of Its Anti-Tumor ActivityPubmed: 30699956
- Clinical significance of soluble programmed cell death-1 and soluble programmed cell death-ligand 1 in patients with locally advanced rectal cancer treated …Pubmed: 30807610
- Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control StudyPubmed: 32085544

 
         
    
     
                 
                 
                             
                