Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 199.00 US$ 498.00 US$ 996.00 US$ 2,988.00 US$ 7,470.00
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Overview

Properties

Product No.RPE189Ra01
Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategoryEnzyme & Kinase

Source Prokaryotic expression, Host E.coli
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationSecreted, Lysosome, Cytoplasm, Golgi apparatus, Endoplasmic reticulum lumen, Endosome
Molecular Mass 58.1kDa, Accurate 58kDa(Analysis of differences refer to the manual)
Residues & TagsTrp164~Phe428 with N-terminal His and GST Tag
Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits Freeze-dried powder, Purity > 90%
Isoelectric Point5.9

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Packages (Simulation)
Packages (Simulation)

Figure . Gene Sequencing (extract)

SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markerspubmed:28409410
Autocrine effects of PCSK9 on cardiomyocytesPubmed: 33169229
Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans33407555
MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice33775647
Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders34533801
Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's diseasePubmed:35502687