Recombinant Renalase (RNLS) Rattus norvegicus (Rat) Recombinant protein

MAO-C; C10orf59; FAD-Dependent Amine Oxidase; Monoamine oxidase-C; alpha-NAD(P)H oxidase/anomerase

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 18.5kDa, Accurate 19kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla18~Ser150 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point6.9
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  • Recombinant Renalase (RNLS) Packages (Simulation)
  • Recombinant Renalase (RNLS) Packages (Simulation)
  • RPC845Ra01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Renalase, kidney function, and markers of endothelial dysfunction in renal transplant recipientsCartelcolor: source
  • Renalase, Stroke, and Hypertension in Hemodialyzed PatientsPubMed: 22583169
  • Renalase in peritoneal dialysis patients is not related to blood pressure, but to dialysis vintage.Pdiconnect: Source
  • Vascular adhesion protein-1 and renalase in regard to diabetes in hemodialysis patientsPubMed: PMC3542495
  • Circulating Levels of Renalase, Norepinephrine, and Dopamine in Dialysis PatientsPubmed: 23530612
  • VAP-1 in chronic kidney disease and diabetic kidney diseaseCzytelniamedyczna: Source
  • The relationship between dopamine and renalase in type 2 diabetic patients with and without diabetic nephropathyPubmed: 15365253
  • Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients.Pubmed: 24599883
  • Renalase, a novel enzyme involved in blood pressure regulation, is related to kidney function but not to blood pressure in hemodialysis patients.Pubmed: 22539018
  • Renalase in hypertension and kidney diseaseOxfordjournals: Source
  • Markers of increased cardiovascular risk in patients with chronic kidney diseaseBiomedcentral:Source
  • Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipientsPubmed:24599883
  • Normal values for urine renalase excretion in childrenPubmed:25060760
  • Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aortaPubmed:25064768
  • Effect of salt intake and potassium supplementation on urinary renalase and serum dopamine levels in Chinese adultsPubmed:25824645
  • Circulating renalase, catecholamines, and vascular adhesionPubMed: 26403854
  • Renalase levels in children with solitary functioning kidneyPubMed: 26713989
  • SP321 RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTSContent: 30
  • PP.27.07: PREHYPERTENSIVE ALTERATIONS OF ARTERIAL AND VENOUS REACTIVITY IN A RAT POLYCYSTIC OVARY SYNDROME MODEL. EFFECTS OF PARALLEL VITAMIN D3 ADMINISTRATIONJhypertension: Abstract
  • PP.27.06: RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS.Jhypertension: Abstract
  • PP.27.04: ENDOTHELIAL DYSFUNCTION AND ARTERIAL HYPERTENSION IN THE WORKING POPULATION (MERIDIAN STUDY).Jhypertension: Abstract
  • Renalase is Removed by Kidneys and During Dialysis – Excess Related to CKD Complications?PubMed: 25515790
  • Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt DietPubMed: 26619289
  • Serum Renalase Levels Correlate with Disease Activity in Lupus NephritisPubMed: 26431044
  • Plasma renalase concentration before and after radiofrequency renal denervation in patients with resistant hypertensionPubMed: 26310184
  • Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.pubmed:27778420
  • PLASMA RENALASE CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION: PRELIMINARY RESULTScontent:31
  • Increased serum renalase in hemodialysis patients: is it related to left ventricular hypertrophy?pubmed:27416751
  • High-performance Liquid Chromatography Measured Metabolites of EndogenousCatecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients.pubmed:27496485
  • Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study.pubmed:27783636
  • Renalase in Children with Glomerular Kidney Diseaseschapter:10.1007
  • Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function452587
  • Rs10887800 renalase gene polymorphism influences the level of circulating renalase in patients undergoing hemodialysis but not in healthy controlspubmed:28372594
  • Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease riskpubmed:28160962
  • Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysispubmed:27822026
  • Aumento de renalasa sérica en pacientes de diálisis peritoneal:¿ está relacionado con el riesgo de enfermedad cardiovascular?10.1016:j.nefro.2016.11.013
  • Relationship between microRNA-146a expression and plasma renalase levels in hemodialyzed patientspubmed:28614373
  • Levels of renalase and advanced oxidation protein products with regard to catecholamines in haemodialysed patientspubmed:28954489
  • Endocan Concentration in Patients With Primary Hypertensionpubmed:29084442
  • RENALASE PLASMA CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION10.1097/01.hjh.0000523893.07419.ae
  • Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathwayspubmed:28448446
  • Transient changes in serum renalase concentration during long-distance running: The case of an amateur runner under continuous training10.7600/jpfsm.6.159
  • Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease‒a cross-sectional studyPubmed:29743680
  • Influence of acute exercise on renalase and its regulatory mechanismPubmed:30056018
  • Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degenerationPubmed:29580721
  • A new method for quantitative determination of renalase based on mass‐spectrometry determination of a proteotypic peptide labeled with stable isotopes10.1002:rcm.8167
  • Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in ratsPubmed:29476431
  • Serum Renalase Levels in Adolescents with Primary HypertensionPubmed:29748702
  • Atorvastatin facilitates protection against contrast-induced nephropathy in patients undergoing coronary angiography via humoral mediators rather than …Pubmed:30008773
  • High urinary kidney injury molecule type 1 level is associated with 12-month adverse cardiovascular events in patients with coronary artery diseasepublication:324522368
  • Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary …Pubmed: 30424498
  • GP23 Percutaneous closure of patent ductus arteriosus: single center experience
  • GP25 Comparison of associations and outcomes of prenatally and postnatally diagnosed right aortic arch: south wales' experience
  • GP24 Serum renalase levels in adolescents with primary hypertension
  • Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot StudyPubmed: 31737132
  • The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertensionPubmed: 32102561
  • Moderate‐intensity exercise increases renalase levels in the blood and skeletal muscle of ratsPubmed: 32053739
  • The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patientsPubmed: 32297799
  • Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic SyndromePubmed: 32982355
  • Nikotinamidadenindinukleotid-Blutplasmawerte sind unabhängig vom kalendarischen und vaskulären Alter in einer Normalkohorte aus der Region Halle-Saalekreis
  • Circulating Renalase as Predictor of Renal and Cardiovascular Outcomes in Pre-Dialysis CKD Patients: A 5-Year Prospective Cohort Study33800219
  • Edited by: Background: Renalase has been implicated in chronic heart failure (CHF); however, nothing is known about renalase discriminatory ability and prognostic …

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