Recombinant Salusin Alpha (SALa) Homo sapiens (Human) Recombinant protein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 21.5kDa, Accurate 29kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer214~Lys241*3 with Two N-terminal Tags, His-tag and SUMO-tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point13.4
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  • Recombinant Salusin Alpha (SALa) Packages (Simulation)
  • Recombinant Salusin Alpha (SALa) Packages (Simulation)
  • Recombinant Salusin Alpha (SALa) Figure. Gene Sequencing (Extract)
  • RPB892Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • The bioactive peptides salusins and apelin–36 are produced in human arterial and venous tissues and the changes of their levels during cardiopulmonary bypassPubMed: 22884920
  • Presence of adropin, nesfatin-1, apelin-12, ghrelins and salusins peptides in the milk, cheese whey and plasma of dairy cowsScienceDirect: S0196978113000533
  • Association of low maternal levels of salusins with gestational diabetes mellitus and with small-for-gestational-age fetuses.PubMed: 23178004
  • Salusin-alpha and -beta expression in heart and aorta with and without metabolic syndromePubmed: 23957705
  • Concentrations of preptin, salusins and hepcidins in plasma and milk of lactating women with or without gestational diabetes mellitusScienceDirect: S0196978113003100
  • Brain, Liver, and Serum Salusin-alpha and-beta Alterations in Sprague-Dawley Rats with or Without Metabolic SyndromePubmed:Pmc4136931
  • Is the serum level of salusin-β associated with hypertension and atherosclerosis in the pediatric population?Pubmed:25245503
  • Serum salusin-α and salusin-β levels in patients with psoriasisPubMed: 26055619
  • Serum salusins levels are increased and correlated positively with cyst size in ovarian endometriomaPubMed: 26008602
  • Increased level of Plasma Salusin-α and Salusin-β in patients with Multiple SclerosisPubmed: 30738876
  • Salusin-α levels are negatively correlated with diastolic blood pressure in children with obesityPubmed: 31486354
  • Salusin-α mitigates diabetic nephropathy via inhibition of the Akt/mTORC1/p70S6K signaling pathway in diabetic ratsPubmed: 31665937
  • Salusin-β is superior to salusin-α as a marker for evaluating coronary atherosclerosisPubmed: 32054363
  • Targeted Delivery of Salusin©\¦Á into Rabbit Carotid Arterial Endothelium Using SonoVue33818784
  • Inhibition of oxidative stress and apoptosis by camel milk mitigates cyclosporine©\induced nephrotoxicity: Targeting Nrf2/HO©\1 and AKT/eNOS/NO pathways34136182

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