Recombinant Transforming Growth Factor Beta 3 (TGFb3) Oryctolagus cuniculus (Rabbit) Recombinant protein

TGF-B3; LAP; Latency-associated peptide

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 15.1kDa, Accurate 16kDa(Analysis of differences refer to the manual)
  • Residues & TagsHis320~Ala418 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point8.5
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  • Recombinant Transforming Growth Factor Beta 3 (TGFb3) Packages (Simulation)
  • Recombinant Transforming Growth Factor Beta 3 (TGFb3) Packages (Simulation)
  • RPB949Rb01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic ApproachesPlosone: Source
  • The immunomodulating effect of seminal plasma on T cellsPubMed: 25799173
  • Influence of vitamin D and transforming growth factor β3 serum concentrations, obesity, and family history on the risk for uterine fibroidspubmed:27743697
  • New scaffolds encapsulating TGF-β3/BMP-7 combinations driving strong chondrogenic differentiationpubmed:28087378
  • Transforme edici büyüme faktörü-beta-1 nötralizan antikoru ve transforme edici büyüme faktörü-beta-3'ün trakeal darlık gelişimi üzerine etkileri10.5606/tgkdc.dergisi.2017.14302
  • Ulipristal acetate decreases transforming growth factor β3 serum and tumor tissue concentrations in patients with uterine fibroidsPubmed:29525690
  • TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degenerationPubmed:29795291
  • The involvement of multifunctional TGF-β and related cytokines in pathogenesis of endometriosisPubmed: 30367890
  • Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose TissuePubmed: 30332637
  • Temporal TGF-β Supergene Family Signalling Cues Modulating Tissue Morphogenesis: Chondrogenesis within a Muscle Tissue Model?Pubmed: 32660137
  • Limited added value of negative pressure wound therapy compared to calcium alginate dressings for second intention healing in a non©\contaminated and?¡­34115409
  • Nanoparticles and Nanostructured Films with TGF-β3: Preparation, Characterization, and Efficacy34378118

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