Recombinant Selenoprotein P1, Plasma (SEPP1) Homo sapiens (Human) Recombinant protein

SEPP; SeP; SEP-P1; SELP

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 25.5kDa, Accurate 33kDa(Analysis of differences refer to the manual)
  • Residues & TagsTyr60~Lys274 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point7.4
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  • Recombinant Selenoprotein P1, Plasma (SEPP1) Packages (Simulation)
  • Recombinant Selenoprotein P1, Plasma (SEPP1) Packages (Simulation)
  • Recombinant Selenoprotein P1, Plasma (SEPP1) Figure . Gene Sequencing (extract)
  • RPB809Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and AtherosclerosisPubMed: 21677040
  • Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver DiseasePubMed: 23439771
  • Trace elements, heavy metals and vitamins in Egyptian school children with iron deficiency anemiaMetapress:Source
  • Selenium and its relationship with selenoprotein P and glutathione peroxidase in children and adolescents with Hashimoto&#039;s thyroiditis and hypothyroidismPubMed: 26854239
  • Selenoprotein P is elevated in individuals with obesity, but is not independently associated withinsulin resistance.pubmed:27524654
  • Acute Overfeeding Does Not Alter Liver or Adipose Tissue-Derived Cytokines in HealthyHumans.pubmed:27832637
  • DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: ashort-term supplementation trial with respect to GPX1 and SEPP1 polymorphism.pubmed:26658762
  • Evaluation of the Relationship Between Insulin Resistance and Selenoprotein P in Patients with Polycystic Ovary SyndromeDOI: 10.14744/scie.2017.87597
  • Serum selenium and selenoprotein-P levels in autoimmune thyroid dieases patients in a select center a transversal studyDOI: 10.1590/2359-3997000000309
  • Selenium, selenoproteins and selenometabolites in mothers and babies at the time of birthpubmed:28534447
  • Biomarkers of selenium status and antioxidant effect in workers occupationally exposed to mercuryPubmed:29895371
  • Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available KitsPubmed:29709922
  • Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitusPubmed: 30470912
  • Selenium Levels in Community Dwellers with Type 2 Diabetes MellitusPubmed: 30725267
  • Can hepatokines be regarded as novel non-invasive serum biomarkers of intrahepatic lipid content in obese children?Pubmed: 30921653
  • Acute swimming exercise, but not exposure to moderate hypoxic conditions reduces circulating selenoprotein P levels in short-term, high-fat diet-fed ratsPubmed: 31236416
  • Selenium and selenoprotein P in nonalcoholic fatty liver diseasePubmed: 31493247
  • Soil Selenium Concentration and Residents Daily Dietary Intake in a Selenosis Area: A Preliminary Study in Yutangba Village, Enshi City, ChinaPubmed: 32909074
  • Higher Serum Selenoprotein P Level as a Novel Inductor of Metabolic Complications in PsoriasisPubmed: 32605214
  • Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function
  • Selenium–GPX4 axis protects follicular helper T cells from ferroptosis34413521
  • Selenoprotein P-1 (SEPP1) as An Early Biomarker of Acute Kidney Injury in Patients Undergoing Cardiopulmonary Bypass

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