Recombinant Spondin 2 (SPON2)

DIL1; Mindin; M-spondin; Extracellular Matrix Protein; Differentially expressed in cancerous and non-cancerous lung cells 1

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 172.00 US$ 430.00 US$ 860.00 US$ 2,580.00 US$ 6,450.00
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Overview

Properties

Product No.RPF396Hu01
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategorySignal transduction

Source Prokaryotic expression, Host E.coli
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationSecreted
Molecular Mass 53.1kDa, Accurate 54kDa(Analysis of differences refer to the manual)
Residues & TagsSer119~Val331 with N-terminal His and GST Tag
Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Traits Freeze-dried powder, Purity > 90%
Isoelectric Point5.6

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Packages (Simulation)
Packages (Simulation)

Figure . Gene Sequencing (extract)

SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

Spondin-2, a secreted extracellular matrix protein, is a novel diagnostic biomarker for prostate cancerPubmed: 23665271
SP136EVALUATION OF SERUM SPONDIN 2 LEVELS IN THE DIFFERENT ETIOLOGIES OF GLOMERULAR DISEASESContent: 30
Evaluation of Serum Spondin 2 Levels in the Different Stages of Type 2 Diabetic NephropathyPubMed: 25973958
The extracellular matrix protein mindin attenuates colon cancer progression by blocking angiogenesis via Egr-1-mediated regulationpubmed:28991232
Study of human T21 placenta suggests a potential role of mesenchymal spondin-2 in placental vascular developmentPubmed: 30715257
Mindin serves as a tumour suppressor gene during colon cancer progression through MAPK/ERK signalling pathway in micePubmed: 32614521