Recombinant Urocortin 2 (UCN2) Homo sapiens (Human) Recombinant protein

URP; SRP; UCN-II; UCNII; Stresscopin-Related Peptide; Urocortin-related peptide

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 11.3kDa, Accurate 13/14/17kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal20~Cys112 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point11.5
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  • Recombinant Urocortin 2 (UCN2) Packages (Simulation)
  • Recombinant Urocortin 2 (UCN2) Packages (Simulation)
  • Recombinant Urocortin 2 (UCN2) Figure. Gene Sequencing (Extract)
  • RPC585Hu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • High-Sensitivity Sandwich ELISA for Plasma NT-proUcn2: Plasma Concentrations and Relationship to Mortality in Heart Failure.Pubmed:27127183
  • Urocortins: Actions in health and heart failurepubmed:28887029
  • Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertensionPubmed:29584808
  • Glucocorticoid withdrawal affects stress‐induced changes in urocortin 2 gene expression in the rat adrenal medulla and brainPubmed:29604138
  • Evaluation of Serum Urocortin 2 Levels in Patients with HypertensionPubmed: 31925709
  • Urocortin-2 in acute heart failure: role as a marker of volume overload and pulmonary hypertension33994037

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