Recombinant Vanin 1 (VNN1) Mus musculus (Mouse) Recombinant protein

Pantetheinase; Pantetheine hydrolase; Tiff66; Vascular non-inflammatory molecule 1

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 13.8kDa, Accurate 14kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal390~Ile503 (Accession # Q9Z0K8) with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point7.05
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  • Recombinant Vanin 1 (VNN1) Packages (Simulation)
  • Recombinant Vanin 1 (VNN1) Packages (Simulation)
  • RPC598Mu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Vanin-1; a potential biomarker for nephrotoxicant-induced renal injuryScienceDirect: S0300483X11003234
  • Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injuryAspet: 192807
  • Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury.PubMed: 22399813
  • Early detection of renal injury using urinary vanin-1 in rats with experimental colitisPubMed: 23307618
  • Effects of Exercise and Ferula Gummosa on Apelin of Cardiac and Kidney Tissues in L-NAME induced Hypertension in RatsJm.um: Source
  • Value of vanin-1 assessment in adult patients with primary immune thrombocytopeniaPubmed: 23534352
  • Early detection of renal injury using urinary vanin-1 in rats with experimental colitis.Pubmed: 23307618
  • Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty ratsSagepub:Source
  • The effect of activated charcoal on adenine-induced chronic renal failure in ratsPubmed:24412558
  • Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intakePubMed: 26376947
  • Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell BalancePubMed: 26253296
  • Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinomaPubmed:27317936
  • Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of micePubmed:26850371
  • Citrate attenuates vascular calcification in chronic renal failure rats.pubmed:28332248
  • Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats.pubmed:29027259
  • Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats …Pubmed:29550811
  • Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of HydronephrosisPubmed: 30332759
  • Involvement of Vanin-1 in Ameliorating Effect of Oxidative Renal Tubular Injury in Dahl-Salt Sensitive RatsPubmed: 31514290
  • Urinary vanin‐1 associated with chronic kidney disease in hypertensive patients: A pilot studyPubmed: 32869948
  • Association of urinary vanin©\1 with kidney function decline in hypertensive patients34029440
  • Plasma vanin-1 as a novel biomarker of sepsis for trauma patients: a prospective multicenter cohort study33624223

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