Prothrombin Fragment 1+2 (F1+2) - Molecular Marker for Early Diagnosis of Thrombotic Diseases

CLOUD-CLONE CORP.(CCC)

Prothrombin Fragment 1+2(F1+2) is stable degradation product when the prothrombin is activated to thrombin. The F1+2 level in blood can reflect the activation level of thrombin in early stage, which can be used to diagnose the prethrombotic state & thrombotic diseases, remedy these diseases and monitor the efficacy. 

Take human F1+2 for example, the intrinsic and extrinsic pathways activate factor X to Xa, which removes the activation peptide and cleaves the remaining part of prothrombin into light and heavy chains by cutting the peptide bonds between Arg327-Thr328 and Arg363-Ile364 at same time, and then the F1+2(Ala44~Arg327) is released. While the thrombin can act on the prothrombin to release F1(ala44~Phe198) and F2(Ser199~Arg327), shown in Fig.1. 

Cloud-Clone Corp. has developed a serial of products for F1+2. For researchers in labs, products include primer pairs, recombinant proteins, specific antibodies and immunoassay kits, etc. As to industrial customers, antibody pairs and DIY kits are provided. What about clinical researches? The IVD raw materials are recommended. The product list is shown below, please check it. Welcome to consult and purchase our products!


CATALOG NO.ORGANISM SPECIESPRODUCT NAMEAPPLICATIONS
Increment ServicePGA710Hu01Homo sapiens (Human)Primer Pair for Prothrombin Fragment 1+2 (F1+2)PCR
PGA710Mu01Mus musculus (Mouse)Primer Pair for Prothrombin Fragment 1+2 (F1+2)PCR
PGA710Ra01Rattus norvegicus (Rat)Primer Pair for Prothrombin Fragment 1+2 (F1+2)PCR
ProteinsRPA710Hu01Homo sapiens (Human)Recombinant Prothrombin Fragment 1+2 (F1+2)Positive Control; Immunogen; SDS-PAGE; WB.
RPA710Mu01Mus musculus (Mouse)Recombinant Prothrombin Fragment 1+2 (F1+2)Positive Control; Immunogen; SDS-PAGE; WB.
RPA710Ra01Rattus norvegicus (Rat)Recombinant Prothrombin Fragment 1+2 (F1+2)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAA710Hu01Homo sapiens (Human)Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC; IP.
LAA710Hu71Homo sapiens (Human)Biotin-Linked Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC.
MAA710Hu21Homo sapiens (Human)Monoclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC; IP.
LAA710Hu72Homo sapiens (Human)Biotin-Linked Monoclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC.
PAA710Mu01Mus musculus (Mouse)Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC; IP.
PAA710Ra01Rattus norvegicus (Rat)Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC; IP.
LAA710Ra81Rattus norvegicus (Rat)FITC-Linked Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC; IF.
LAA710Ra71Rattus norvegicus (Rat)Biotin-Linked Polyclonal Antibody to Prothrombin Fragment 1+2 (F1+2)WB; IHC; ICC.
Assay KitsSEA710HuHomo sapiens (Human)ELISA Kit for Prothrombin Fragment 1+2 (F1+2)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA710HuHomo sapiens (Human)CLIA Kit for Prothrombin Fragment 1+2 (F1+2)Chemiluminescent immunoassay for Antigen Detection.
HEA710HuHomo sapiens (Human)High Sensitive ELISA Kit for Prothrombin Fragment 1+2 (F1+2)Enzyme-linked immunosorbent assay for Antigen Detection.
SEA710MuMus musculus (Mouse)ELISA Kit for Prothrombin Fragment 1+2 (F1+2)Enzyme-linked immunosorbent assay for Antigen Detection.
SCA710RaRattus norvegicus (Rat)CLIA Kit for Prothrombin Fragment 1+2 (F1+2)Chemiluminescent immunoassay for Antigen Detection.
SEA710RaRattus norvegicus (Rat)ELISA Kit for Prothrombin Fragment 1+2 (F1+2)Enzyme-linked immunosorbent assay for Antigen Detection.
SEA710PoSus scrofa; Porcine (Pig)ELISA Kit for Prothrombin Fragment 1+2 (F1+2)Enzyme-linked immunosorbent assay for Antigen Detection.
Antibody PairsPSA710Hu01Homo sapiens (Human)Antibody Pair for Troponin I Type 1, Slow Skeletal (TNNI1)ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
PSA710Mu01Mus musculus (Mouse)Antibody Pair for Troponin I Type 1, Slow Skeletal (TNNI1)ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
PSA710Ra01Rattus norvegicus (Rat)Antibody Pair for Troponin I Type 1, Slow Skeletal (TNNI1)ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
PSA710Po01Sus scrofa; Porcine (Pig)Antibody Pair for Troponin I Type 1, Slow Skeletal (TNNI1)ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
Assay Kit DIY MaterialsKSA710Hu01Homo sapiens (Human)ELISA Kit DIY Materials for Prothrombin Fragment 1+2 (F1+2)Main materials for "Do It(ELISA Kit) Yourself"
KSA710Mu01Mus musculus (Mouse)ELISA Kit DIY Materials for Prothrombin Fragment 1+2 (F1+2)Main materials for "Do It(ELISA Kit) Yourself"
KSA710Ra01Rattus norvegicus (Rat)ELISA Kit DIY Materials for Prothrombin Fragment 1+2 (F1+2)Main materials for "Do It(ELISA Kit) Yourself"
KSA710Po01Sus scrofa; Porcine (Pig)ELISA Kit DIY Materials for Prothrombin Fragment 1+2 (F1+2)Main materials for "Do It(ELISA Kit) Yourself"
IVD Raw MaterialsRSA710Hu21Homo sapiens (Human)Anti-Prothrombin Fragment 1+2 (F1+2) Monoclonal Antibody for IVD Raw MaterialELISA; WB; IHC; Other  Immunoassays.
RSA710Hu01Homo sapiens (Human)Anti-Prothrombin Fragment 1+2 (F1+2) Polyclonal Antibody for IVD Raw MaterialELISA; WB; IHC; Other  Immunoassays.

Table 1. Serial products for Prothrombin Fragment 1+2

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