Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1) Monoclonal Antibody Homo sapiens (Human) Protein, Antibody, Assaykit, Service

ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2

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Overview
Properties
  • Ig Isotype IgG, Clone Number C5
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Excitation Laser
  • Vol. per test
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid
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  • Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1) Monoclonal Antibody Packages (Simulation)
  • Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1) Monoclonal Antibody Packages (Simulation)
  • Anti-Beta-Site APP Cleaving Enzyme 1 (bACE1) Monoclonal Antibody Human Jurkat cell line was fixed with 2% paraformaldehyde (10 min) , permeabilised with 0.1% BSA-Triton X-100,then stained with 10µg/ml mouse Anti-human bACE1 Monoclonal Antibody (Catalog FAA718Hu02, red histogram) or Isotype control antibody (Catalog IS067-Mu01, green histogram), followed by 1µg/ml FITC-conjugated Anti-mouse IgG Secondary Antibody (Catalog SAA544Mu18).
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Usage

Flow cytometry: 10µg/ml;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Giveaways

Citations

  • Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 micepubmed:29292421
  • EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation10.1016/j.jff.2017.12.016
  • Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat dietPubmed:29986309
  • Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in micePubmed: 32522471
  • Effects of Alcohol Intake on Cognitive Function and ¦Â-amyloid Protein in APP/PS1 Transgenic Mice33737111

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