Anti-Exportin 1 (XPO1) Polyclonal Antibody

Exp1; CRM1 Homolog,Yeast; Chromosome region maintenance 1 protein homolog

UOM
1. 25test
2. 50test
3. 100test
4. 200test
5. 500test
FOB US$ 132.00 US$ 220.00 US$ 352.00 US$ 440.00 US$ 770.00
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Overview

Properties

Product No.FAC258Hu01
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsFlow cytometry.
Research use only
Downloadn/a
CategorySignal transduction Infection immunity Immunodeficiency

Ig Type IgG, Potency n/a
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
LabelNone
Excitation LaserNone
Vol. per test1-5 µl
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid

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Packages (Simulation)
Packages (Simulation)

Human K562 cell line was fixed with 2% paraformaldehyde (10 min) , permeabilised with 0.2% BSA-Triton X-100,then stained with 20µg/ml rabbit Anti-human XPo1 Polyclonal Antibody (Catalog FAC258Hu01, red histogram) or Isotype control antibody (Catalog IS067-Rb01, green histogram), followed by 1µg/ml FITC-conjugated Anti-rabbit IgG Secondary Antibody (Catalog SAA544Rb18).

ISO9001: 2008, ISO13485: 2003 Registered

Usage

For flow cytometry, the suggested use of this reagent is 1-5 µl per 10^6 cells in 100 µl volume.
Optimal working dilutions could be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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Citations

Inactivation of the p53–KLF4–CEBPA Axis in Acute Myeloid LeukemiaPubMed: 26408402
Inactivation of the p53–KLF8–CEBPA Axis in Acute Myeloid LeukemiaPubMed: 26408402
Mahendra Seervi, S. Sumi, Aneesh Chandrasekharan, Abhay K. Sharma &Doi: 10.1007/s13402-019-00451-1
Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathwayPubmed: 31147963
XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial InfarctionPubmed: 31768947
Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry34472763