Polyclonal Antibody to Annexin A2 (ANXA2) Homo sapiens (Human) Polyclonal antibody

ANX-A2; ANX2L4; CAL1H; LIP2; LPC2; LPC2D; P36; PAP-IV; Protein I; Chromobindin-8; Calpactin-1 heavy chain; Lipocortin II; Placental anticoagulant protein IV

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPB944Hu01-Recombinant Annexin A2 (ANXA2)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 0.48mg/mL
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  • Polyclonal Antibody to Annexin A2 (ANXA2) Packages (Simulation)
  • Polyclonal Antibody to Annexin A2 (ANXA2) Packages (Simulation)
  • Polyclonal Antibody to Annexin A2 (ANXA2) DAB staining on IHC-P; Sample: Human Placenta Tissue Primary Ab: 10µg/ml Rabbit Anti-Human ANXA2 Antibody Control: Used PBS instead of primary antibody Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Annexin A2 (ANXA2) DAB staining on IHC-P;
    Sample: Porcine Uterus Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Human ANXA2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Annexin A2 (ANXA2) DAB staining on IHC-P;
    Sample: Porcine Small intestine Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Human ANXA2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Annexin A2 (ANXA2) DAB staining on IHC-P;
    Sample: Porcine Liver Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Human ANXA2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Annexin A2 (ANXA2) DAB staining on IHC-P;
    Sample: Porcine Lung Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Human ANXA2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • PAB944Hu01.jpg Figure. Western Blot; Sample: Recombinant ANXA2, Human.
  • Polyclonal Antibody to Annexin A2 (ANXA2) Figure. Western Blot; Sample: Rat Placenta Tissue.
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against ANXA2. It has been selected for its ability to recognize ANXA2 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat)

Giveaways

Citations

  • Subcellular proteome analysis unraveled annexin A2 related to immune liver fibrosisPubMed: 20225235
  • Expression characteristics and diagnostic value of annexin A2 in hepatocellular carcinomaPubMed: PMC3491596
  • Annexin A2 is not a good biomarker for hepatocellular carcinoma in cirrhosisPubMed: PMC3742823
  • Annexin A2 Versus Afp as An Efficient Diagnostic Serum Marker for Hepatocellular CarcinomaGhrnet: Source
  • Serum annexin A2 levels in acute brucellosis and brucellar spondylodiscitisPubmed:24853056
  • Circulating annexin A2 as a biomarker in gastric cancer patients: Correlation with clinical variablesPubmed:25661364
  • Serum Levels of Annexin A2 as a Candidate Biomarker for Hepatic Fibrosis in Patients With Chronic Hepatitis BPubMed: 26587036
  • Up-regulation of annexin A2 expression predicates advanced clinicopathological features and poor prognosis in hepatocellular carcinomaPubMed: 26109000
  • CirculatingPubMed: 25661364
  • Evaluation of annexin A2 and as potential biomarkers for hepatocellular carcinomaPubMed: 26189841
  • Stairs instead of elevators at the workplace decreases PCSK9 levels in a healthy populationPubMed: 26081791
  • Serum Annexin A2 Level Is Associated With Diagnosis and Prognosis in Patients With OralSquamous Cell Carcinoma.pubmed:27889534
  • Assessment of annexin A5 and annexin A2 levels as biomarkers for pre-eclampsia: A pilot study.pubmed:28501283
  • Epigallocatechin gallate induces an up-regulation of LDL receptor accompanied by a reduction of PCSK9 via the annexin A2-independent pathway in HepG2 cells.pubmed:28181408
  • Expression of annexin A2 in adenomyosis and dysmenorrheaPubmed: 31183557
  • Extracellular Vesicles-Based Biomarkers Represent a Promising Liquid Biopsy in Endometrial CancerPubmed: 31842290
  • PLASMA BIOMARKER FOR OVARIAN CANCER
  • Diagnostic Value of Plasma Annexin A2 in Early-Stage High-Grade Serous Ovarian Cancer. Diagnostics 2021, 11, 6933406648
  • Search for Effective Serum Tumor Markers for Early Diagnosis of Hepatocellular Carcinoma Associated with Hepatitis C
  • Bufalin Induced Mitochondrial Dysfunction Promotes Apoptosis of Glioma Cells by Regulating Annexin A2 and DRP1 Proteins
  • Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression34376212

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