Polyclonal Antibody to Biglycan (BGN) Homo sapiens (Human) Polyclonal antibody

DSPG1; PG-S1; PGI; SLRR1A; Biglycan Proteoglycan; Bone/cartilage proteoglycan I

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPJ226Hu02-Recombinant Biglycan (BGN)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Polyclonal Antibody to Biglycan (BGN) Packages (Simulation)
  • Polyclonal Antibody to Biglycan (BGN) Packages (Simulation)
  • Polyclonal Antibody to Biglycan (BGN) DAB staining on IHC-P; Samples: Human Breast cancer Tissue; Primary Ab: 15µg/ml Rabbit Anti-Human BGN Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) DAB staining on IHC-P;
    Samples: Human Liver Tissue;
    Primary Ab: 15µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) DAB staining on IHC-P;
    Samples: Human Prostate Tissue;
    Primary Ab: 15µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) DAB staining on IHC-P;
    Samples: Human Cerebrum Tissue;
    Primary Ab: 15µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) DAB staining on IHC-P;
    Samples: Human Kidney Tissue;
    Primary Ab: 15µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) AF488 staining on IF;
    Sample: HepG2 cell
    Primary Ab: 20µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb11)
  • PAJ226Hu02.jpg Figure. Western Blot; Sample: Recombinant BGN, Human.
  • Polyclonal Antibody to Biglycan (BGN) Western Blot; Sample: Porcine Kidney lysate;
    Primary Ab: 5µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Biglycan (BGN) Western Blot; Sample: Porcine Spleen lysate;
    Primary Ab: 5µg/ml Rabbit Anti-Human BGN Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against BGN. It has been selected for its ability to recognize BGN in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-5µg/mL;
Immunohistochemistry: 5-50µg/mL;
Immunocytochemistry: 5-50µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa; Porcine (Pig)

Giveaways

Citations

  • Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysreCavia (Guinea pig )lation of biglycanPubmed:27295191
  • Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing.pubmed:29022912
  • Degenerative aortic valve disease and diabetes: Implications for a link between proteoglycans and diabetic disorders in the aortic valvePubmed: 30563371
  • Die Rolle der extrazellulären Matrix in der degenerativen Aortenklappenerkrankung unter dem Einfluss von Diabetes
  • Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans33407555
  • Inhibition of Stromal Biglycan Promotes Normalization of the Tumor Microenvironment and Enhances Chemotherapeutic Efficacy33966638

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