Polyclonal Antibody to Cartilage Oligomeric Matrix Protein (COMP)    
    
MED; EDM1; EPD1; PSACH; THBS5; TSP-5; Pseudoachondroplasia,Epiphyseal Dysplasia 1,Multiple; Thrombospondin 5
Overview
Properties
- Product No.PAB197Hu01
 - Organism SpeciesHomo sapiens (Human) Same name, Different species.
 - ApplicationsWB
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only - DownloadInstruction Manual
 - CategoryMetabolic pathwayBone metabolism
 
- SourcePolyclonal antibody preparation, Host Rabbit
 - Ig Type IgG, Potency n/a
 - PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
 - LabelNone
 - Immunogen RPB197Hu01-Recombinant Cartilage Oligomeric Matrix Protein (COMP)
 - Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 - TraitsLiquid, Concentration 0.5mg/mL
 
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Specifity
The antibody is a rabbit polyclonal antibody raised against COMP. It has been selected for its ability to recognize COMP in immunohistochemical staining and western blotting.
Usage
            Western blotting: 0.01-3µg/mL;
Optimal working dilutions must be determined by end user.        
Storage
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Organism Species More: Sus scrofa; Porcine (Pig)Giveaways
Increment services
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                    Antibody Labeling Customized Service
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                    Protein A/G Purification Column
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                    Staining Solution for Cells and Tissue
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                    Positive Control  for Antibody
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                    Tissue/Sections Customized Service
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                    Phosphorylated Antibody Customized Service
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                    Western Blot (WB) Experiment Service
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                    Immunohistochemistry (IHC) Experiment Service
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                    Immunocytochemistry (ICC) Experiment Service
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                    Flow Cytometry (FCM) Experiment Service
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                    Immunoprecipitation (IP) Experiment Service
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                    Immunofluorescence (IF) Experiment Service
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                    Buffer
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                    DAB Chromogen Kit
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                    SABC Kit
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                    Long-arm Biotin Labeling Kit
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                    Real Time PCR Experimental Service
                                 
Citations
- Genetic analysis and serum level of cartilage oligomeric matrix protein in patients with pseudoachondroplasia CMJ: 201082337960590
 - Decreased Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutationpubmed:29104872
 - Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate‑induced osteoarthritis ratspubmed:29067461
 - Cartilage Oligomeric Matrix Protein Levels in Synovial Fluid in Patients With Primary Knee Osteoarthritis And Healthy Controls: A Preliminary Comparative Analysis With Serum Cartilage Oligomeric Matrix Proteindoi: 10.5606/ArchRheumatol.2017.6220
 - Cartilage Oligomeric Matrix Protein Levels in Type 2 Diabetes Associated with Primary Knee Osteoarthritis PatientsPubmed: 30526057
 - The relationship between the serum and synovial fluid osteopontin (OPN), cartilage oligomeric matrix protein (COMP), and the severity of knee osteoarthritis …
 - Diagnostic Accuracy of Cartilage Oligomeric Matrix Protein (COMP), for Cartilage Damage in Rheumatoid Arthritis
 
