Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) Homo sapiens (Human) Polyclonal antibody

CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPA940Hu01-Recombinant Chemokine C-X-C-Motif Receptor 4 (CXCR4)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 0.5mg/ml
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  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) Packages (Simulation)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) Packages (Simulation)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) DAB staining on IHC-P; Sample: Human Stomach Tissue; Primary Ab: 10µg/ml Rabbit Anti-Human CXCR4 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) DAB staining on IHC-P;
    Sample: Human Lung cancer Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Human CXCR4 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) DAB staining on IHC-P;
    Sample: Human Kidney Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Human CXCR4 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) DAB staining on IHC-P;
    Sample: Rat Cardiac Muscle Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human CXCR4 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) DAB staining on IHC-P;
    Sample: Rat Lymph node Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human CXCR4 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chemokine C-X-C-Motif Receptor 4 (CXCR4) AF488 staining on IF;
    Sample: Jurkat cell
    Primary Ab: 20µg/ml Rabbit Anti-Human CXCR4 Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb11)
  • PAA940Hu01.jpg Figure. Western Blot; Sample: Recombinant CXCR4, Human.
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against CXCR4. It has been selected for its ability to recognize CXCR4 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Rattus norvegicus (Rat)

Giveaways

Citations

  • Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate modelWiley: source
  • Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular CarcinomaPubMed: PMC3589458
  • The non-alcoholic fraction of beer increases stromal cell derived factor 1 and the number of circulating endothelial progenitor cells in high cardiovascular risk subjects: A randomized clinical trialPubmed:24530788
  • Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depressionPubmed:25150002
  • Serum concentrations of chemokines (CCL-5 and CXCL-12), chemokine receptors (CCR-5 and CXCR-4), and IL-6 in patients with posttraumatic stress disorder and avoidant personality disorderPubMed: 26481549
  • A study of chemokines, chemokine receptors and interleukin-6 in patients with panic disorder, personality disorders and their co-morbidityPubmed:27208878
  • Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonistspmc:PMC4866076
  • Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison …Pubmed:29670878

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