Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Homo sapiens (Human) Polyclonal antibody

GP39; CHI3-L1; YKL40; Chondrex; Chitinase 3-Like 1; Chondrocyte Protein YKL40; 39 kDa synovial protein

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPB463Hu01-Recombinant Chitinase-3-like Protein 1 (CHI3L1)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 0.49mg/mL
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  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Packages (Simulation)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Packages (Simulation)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 20µg/ml Rabbit Anti-Human GP39 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) DAB staining on IHC-P;
    Samples: Human Liver cancer Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GP39 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) DAB staining on IHC-P;
    Samples: Human Rectum Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GP39 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) DAB staining on IHC-P;
    Samples: Human Breast cancer Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GP39 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Vector Red staining on IHC-P;
    Samples: Human Liver Tissue;
    Primary Ab: 5µg/ml Rabbit Anti-Human GP39 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Vector Red staining on IHC-P;
    Samples: Human Lung Tissue;
    Primary Ab: 5µg/ml Rabbit Anti-Human GP39 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
  • PAB463Hu01.jpg WB Image
  • Polyclonal Antibody to Chitinase-3-like Protein 1 (CHI3L1) Figure. Western Blot; Sample: Human Serum.
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against CHI3L1. It has been selected for its ability to recognize CHI3L1 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Serum YKL-40: a potential biomarker for psoriasis or endothelial dysfunction in psoriasis?Pubmed:25421412
  • YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatmentPubmed:25578181
  • Assessment of pulsed electromagnetic field therapy with Serum YKL‐40 and ultrasonography in patients with knee osteoarthritisPubMed: 25955771
  • YKL-40 expression in chronic obstructive pulmonary disease: relation to acute exacerbations and airway remodelingPubmed:27013031
  • Compositions and Methods for Diagnosing Lung Cancery2016:0077095.html
  • Chronic obstructive pulmonary disease (COPD)--from biomarkers to clinical phenotypesISBN:978-951-51-4039-5
  • YKL-40 is a local marker for inflammation in patients with pseudoexfoliation syndromePubmed: 30560917
  • Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of Chi3l1 expressionPubmed: 31002152
  • Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic PatientsPubmed: 31717649
  • Oligodendrocyte Progenitor Cells Increase Chi3l1 Secretion in Exosome to Activate Myh9 and Promote Proliferation through Connexin47 Connected to …
  • High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease33814903

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