Monoclonal Antibody to Granzyme B (GZMB) Homo sapiens (Human) Monoclonal antibody

GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number D2
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPA600Hu01-Recombinant Granzyme B (GZMB)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Monoclonal Antibody to Granzyme B (GZMB) Packages (Simulation)
  • Monoclonal Antibody to Granzyme B (GZMB) Packages (Simulation)
  • Monoclonal Antibody to Granzyme B (GZMB) IHC Images
  • MAA600Hu22.jpg Western Blot; Sample: Human PBMC cell lysate Primary Ab: 0.04µg/ml Mouse Anti-Human GZMB Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against GZMB. It has been selected for its ability to recognize GZMB in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70Pubmed:24691976
  • Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 MelanomaPubmed:24818259
  • Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopicdermatitis.pubmed:27686401
  • Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatmentPubmed:29983866
  • A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumorsPubmed: 31695790
  • Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma34377237

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