Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11) Mus musculus (Mouse) Polyclonal antibody

BMP11; Bone morphogenetic protein 11

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Polyclonal Antibody to Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against GDF11. It has been selected for its ability to recognize GDF11 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic micePubMed: 26317549
  • TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Micepubmed:27611336
  • GDF11 is increased in patients with myelodysplastic syndromefiles:ijcep0024948.pdf
  • GDF11 does not improve the palmitate induced insulin resistance in C2C12.pubmed:28485800
  • РОЛЬ ДИФФЕРЕНЦИРОВОЧНОГО ФАКТОРА РОСТА 11 (GDF11) В РЕГУЛЯЦИИ ЛИПИДНОГО ОБМЕНА И КАРДИОГЕМОДИНАМИЧЕСКИХ ФУНКЦИЙ …Cyberleninka:Source
  • GDF11 is increased in patients with aplastic anemiaPubmed: 30727851
  • GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs33764670
  • The relationship between transforming growth factor β superfamily members (GDF11 and BMP4) and lumbar spine bone mineral density in postmenopausal Chinese …34417839
  • Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and …34336096

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