Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) Rattus norvegicus (Rat) Monoclonal antibody

VEGF-C; Flt4-L; VRPL; Vascular Endothelial Growth Factor-Related Protein

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number D3
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPA145Ra01-Recombinant Vascular Endothelial Growth Factor C (VEGFC)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) Packages (Simulation)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) Packages (Simulation)
  • MAA145Ra22.jpg Figure. Western Blot; Sample: Recombinant VEGFC, Rat.
  • Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) Western Blot; Sample: Rat Thymus lysate
    Primary Ab: 2μg/ml Mouse Anti-Rat VEGFC Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against VEGFC. It has been selected for its ability to recognize VEGFC in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Homo sapiens (Human)

Giveaways

Citations

  • Alternatively activated RAW264. 7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinomaPubMed: 19241443
  • Expression of COX-2 and VEGF-C in cholangiocarcinomas at different clinical and pathological stagesPubMed: 26125824
  • Fenofibrate inhibits the expression of VEGFC and VEGFR-3 in retinal pigmental epithelial cells exposed to hypoxiaPubMed: 26622498
  • IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via MacrophagesPubMed: 26608451
  • Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells.pubmed:27383632
  • RNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth andinduces apoptosis in mouse breast cancer in vitro and in vivo.pubmed:27895746
  • Characterization of isolated liver sinusoidal endothelial cells for liver bioengineeringPubmed:29582235
  • Effects of diphyllin as a novel V-ATPase inhibitor on TE-1 and ECA-109 cellsPubmed:29328465
  • Dynamic signature of lymphangiogenesis during acute kidney injury and chronic kidney diseasePubmed: 31019289
  • Isotretinoin does not alter VEGF-A and VEGF-C levels: Do retinoids behave differently in dose-dependent and/or in vivo/in vitro conditions?Pubmed: 32722957

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