Biotin-Linked Polyclonal Antibody to Hemojuvelin (HJV) Homo sapiens (Human) Labelled antibody

HFE2; HFE2A; HJV; JH; RGMC; hemochromatosis type 2(Juvenile); Haemojuvelin; RGM domain family member C

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Overview
Properties
  • SourceAntibody labeling
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelBiotin
  • Original Antibody n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Biotin-Linked Polyclonal Antibody to Hemojuvelin (HJV) Packages (Simulation)
  • Biotin-Linked Polyclonal Antibody to Hemojuvelin (HJV) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against HJV. It has been selected for its ability to recognize HJV in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Effect of Iron Overload and Iron Deficiency on Liver Hemojuvelin ProteinPubMed: PMC3356351
  • Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary ReportPubMed: 25881778
  • Soluble hemojuvelin in transfused and untransfused thalassaemic subjectsdoi:10.1111
  • The secret war against counterfeit sciencepubmed:28492262
  • Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgeryPubmed:29699579
  • Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac SurgeryPubmed:29386545
  • The functional role of hemojuvelin in acute ischemic strokePubmed: 31307288
  • Oxidative damage and iron dyshomeostasis in thalassemic patients
  • Caffeine and alcohol-friends or foes of human iron stores?Pubmed:35063815
  • Urinary Biomarkers Can Predict Weaning From Acute Dialysis Therapy in Critically Ill PatientsPubmed:35311928
  • The Relationships among Plasma Fetuin-B, Thyroid Autoimmunity, and Fertilization Rate In Vitro Fertilization and Embryo TransferPubmed:35340679

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