Biotin-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)    
    
HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1
Overview
Properties
- Product No.LAA785Mu71
 - Organism SpeciesMus musculus (Mouse) Same name, Different species.
 - ApplicationsWBIf the antibody is used in flow cytometry, please check FCM antibodies.
Research use only - Downloadn/a
 - CategoryTumor immunityInfection immunityKidney biomarker
 
- SourceAntibody labeling
 - Ig Type IgG, Potency n/a
 - PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
 - LabelBiotin
 - Original Antibody n/a
 - Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
 - TraitsLiquid, Concentration 500µg/mL
 
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Specifity
The antibody is a rabbit polyclonal antibody raised against Kim1. It has been selected for its ability to recognize Kim1 in immunohistochemical staining and western blotting.
Usage
            
                        Western blotting: 0.2-2µg/mL;1:250-2500
                        
 Immunohistochemistry: 5-20µg/mL;1:25-100
                        
 Immunocytochemistry: 5-20µg/mL;1:25-100
                        
 Optimal working dilutions must be determined by end user.
                        
        
Storage
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Organism Species More: Homo sapiens (Human)Giveaways
Increment services
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                    Protein A/G Purification Column
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                    Staining Solution for Cells and Tissue
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                    Positive Control  for Antibody
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                    Tissue/Sections Customized Service
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                    Phosphorylated Antibody Customized Service
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                    Western Blot (WB) Experiment Service
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                    Immunohistochemistry (IHC) Experiment Service
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                    Immunocytochemistry (ICC) Experiment Service
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                    Flow Cytometry (FCM) Experiment Service
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                    Immunoprecipitation (IP) Experiment Service
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                    Immunofluorescence (IF) Experiment Service
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                    Buffer
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                    DAB Chromogen Kit
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                    SABC Kit
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                    Real Time PCR Experimental Service
                                 
Citations
- Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxicationPubMed: 19827907
 - KIM-1 and NGAL: new markers of obstructive nephropathySpringerLink: v461592787w5488x
 - Urinary Neutrophil Gelatinase-Associated Lipocalin at Birth Predicts Early Renal Function in Very Low Birth Weight InfantsLWW: 10000
 - Markers of kidney function in the elderly in relation to the new CKD-EPI formula for estimation of glomerular filtration rateAMS: source
 - Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product contentPubMed: 23046363
 - Comprehensive assessment of nephrotoxicity of intravenously administered sodium-oleate-coated ultra-small superparamagnetic iron oxide (USPIO) and titanium dioxide (TiO(2)) nanoparticles in rats.PubMed: 23272807
 - A Mouse Diversity Panel Approach Reveals the Potential for Clinical Kidney Injury Due to DB289 Not Predicted by Classical Rodent ModelsPubMed: PMC3498743
 - Interleukin 18 as a Marker of Chronic Nephropathy in Children after Anticancer TreatmentHindawi: 369784
 - Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical ModelHindawi: 413853
 - Kidney injury molecule-1: a urinary biomarker for contrast induced acute kidney injury.Iiste: Source
 - Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplantPubmed: 24325180
 - Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content.Pubmed: 23046363
 - The Renal Effects of Vanadate Exposure: Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary StudiesHindawi: 740105
 - Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat modelPubmed:25476829
 - Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty ratsSagepub:Source
 - 中性粒细胞明胶酶相关脂质运载蛋白、肾损伤分子1和白介素18 在诊断心肺分流术后急性肾损伤中的意义Jcp-Sh:Source
 - Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipientsPubmed:24666430
 - Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-ReperfusionPubmed:24816434
 - SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trialPubmed:24996842
 - The diagnosis of febrile urinary tract infection in children may be facilitated by urinary biomarkersPubmed:25127917
 - Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous CrisisPubmed:25448261
 - Kidney injury molecule-1: A urinary biomarker for contrast-induced acute kidney injuryTmjournals:Source
 - Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitisPubMed: 26191125
 - Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in micePubMed: 26045773
 - Vorinostat protects against calcium oxalate-induced kidney injury in micePubMed: 26095064
 - Role of new biomarkers for predicting renal scarring in vesicoureteral reflux: NGAL, KIM-1, and L-FABPPubMed: 26324091
 - Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosisPubMed: 26096437
 - Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the KidneyPubMed: 26672616
 - Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti‑inflammatory, and anti‑apoptotic activities.Pubmed:27082705
 - Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine modelsPubmed:26908768
 - Kidney Injury Molecule Levels in Type 2 Diabetes MellitusPubmed:27132791
 - Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Modelpmc:PMC4754091
 - Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial HomeostasisPubmed:26822084
 - Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db micePubmed:27226136
 - Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in RatsBarakat812016JALSI28698.pdf
 - Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model.pubmed:28053694
 - Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via itsantioxidant, anti‑inflammatory, and anti‑apoptotic activities.pubmed:27082705
 - Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Micepubmed:29254330
 - Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats.pubmed:29027259
 - Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise10.1159/000481179
 - Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats …Pubmed:29550811
 - Exploring the therapeutic mechanism of Desmodium styracifolium on oxalate crystal-induced kidney injuries using comprehensive approaches based on …Pubmed:29950996
 - Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic NephropathyPubmed:29642511
 - Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed micePubmed:29443547
 - Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in RatsPubmed: 30251228
 - A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1(KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo
 - Urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, N-acetyl-β-D-glucosaminidase levels and mortality risk in septic patients with …Pubmed: 30393493
 - UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal InjuryPubmed: 30381664
 - The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic NephropathyPubmed: 30504713
 - Urine markers of renal tubular injury in idiopathic membranous nephropathy: A cross sectional studyPubmed: 30684459
 - Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicinePubmed: 30871515
 - Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase InhibitorsDoi: BioMed Research International
 - Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascadePubmed: 31197431
 - Effect of Cucumis melo var. flexuosus leaves extract on renal oxidative injury and inflammation in diabetic male albino rats
 - Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixturesPubmed: 31639605
 - page Metabolomics study of fasudil on cisplatin-induced kidney injuryPubmed: 31670380
 - MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injuryPubmed: 31790686
 - Protective effect of saxagliptin against renal ischaemia reperfusion injury in ratsPubmed: 31979992
 - Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin DPubmed: 31943002
 - Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathwayPubmed: 32798557
 - Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology proceduresPubmed: 32557377
 - Can Serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Help in Decision Making for Surgery in Antenatally Dedected …Pubmed: 33139211
 - Ratlarda sodyum florid ile oluşturulan toksikasyonda Karvakol'ün böbrekler üzerine etkisi
 - Rationale and design of the intervention in PHOspholamban RElated CArdiomyopathy STudy (i-PHORECAST)
 - Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers33423326
 - Value of urinary kidney injury molecule-1 levels in predicting acute kidney injury in very low birth weight preterm infants33372811
 - Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury33604384
 - Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide33922959
 - Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI34127536
 - Anti-oxidant impact of Lisinopril and Enalapril against acute kidney injury induced by doxorubicin in male Wistar rats: involvement of kidney injury molecule-133506137
 - Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-¦ÊB/HMGB-1 trajectories34030796
 - Could urinary kidney injury molecule-1 be a good marker in subclinical acute kidney injury in mild to moderate COVID-19 infection?34213713
 - Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental …34169407
 - Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure34820603
 
