Monoclonal Antibody to Aquaporin 4 (AQP4)
HMIWC2; MIWC; WCH4; Mercurial-insensitive water channel
Overview
Properties
- Product No.MAA582Hu29
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
- ApplicationsWB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only - Downloadn/a
- CategorySignal transductionMetabolic pathwayInfection immunityNeuro science
- SourceMonoclonal antibody preparation, Host Mouse
- Ig Isotype IgG2a Kappa, Clone Number C8
- PurificationProtein A + Protein G affinity chromatography
- LabelNone
- Immunogen RPA582Hu01-Recombinant Aquaporin 4 (AQP4)
- Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
- TraitsLiquid, Concentration 1mg/mL
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Specifity
The antibody is a mouse monoclonal antibody raised against AQP4. It has been selected for its ability to recognize AQP4 in immunohistochemical staining and western blotting.
Usage
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
Storage
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Organism Species More: Rattus norvegicus (Rat)Giveaways
Increment services
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Antibody Labeling Customized Service
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Protein A/G Purification Column
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Staining Solution for Cells and Tissue
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Positive Control for Antibody
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Tissue/Sections Customized Service
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Phosphorylated Antibody Customized Service
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Western Blot (WB) Experiment Service
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Immunohistochemistry (IHC) Experiment Service
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Immunocytochemistry (ICC) Experiment Service
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Flow Cytometry (FCM) Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Immunofluorescence (IF) Experiment Service
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Buffer
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DAB Chromogen Kit
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SABC Kit
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Long-arm Biotin Labeling Kit
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Real Time PCR Experimental Service
Citations
- Aquaporins AQP1 and AQP4 in the cerebrospinal fluid of bacterial meningitis patientsScienceDirect: S0304394011012341
- Astrocytic damage is far more severe than demyelination in NMONeurology: 208
- Aquaporin-4 expression in the cerebrospinal fluid in congenital human hydrocephalusPubMed: PMC3651869
- Melanocortin MC4 receptor agonists alleviate brain damage in abdominal compartment syndrome in the ratPubMed: 25616531
- Novel effect of Daflon and low-dose γ-radiation in modulation of thioacetamide-induced hepatic encephalopathy in male albino ratsPubmed:26987350
- Decreased levels of aquaporin-4 in the cerebrospinal fluid of patients with idiopathic intracranial hypertensionPubmed:26853804
- Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus.pubmed:28212403
- Neuron-derived Plasma Exosome Proteins after Remote Traumatic Brain InjuryPubmed: 31441374
- Paeonol Protects Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease33995926
- Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus34597351