Monoclonal Antibody to Caveolin 1 (CAV1) Canis familiaris; Canine (Dog) Monoclonal antibody

VIP21; Caveolae Protein 22kDa

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG, Clone Number n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Caveolin 1 (CAV1) Packages (Simulation)
  • Monoclonal Antibody to Caveolin 1 (CAV1) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against CAV1. It has been selected for its ability to recognize CAV1 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Novel prostate cancer tumour markers in a cell line modelMendelu: source
  • Caveolin-1 as a potential high-risk prostate cancer biomarkerPubMed: 22159333
  • Increased plasma caveolin-1 levels are associated with progression of prostate cancer among Japanese menPubmed: 23645736
  • Decrased sputum caveolin-1 is associated with systemic sclerosis related lung diseasePubmed:24751454
  • Significant Association of Caveolin-1 and Caveolin-2 with Prostate Cancer ProgressionPubMed: 26543085
  • Genomic variant in CAV1 increases susceptibility to coronary artery disease and myocardial infarctionPubmed:26775120
  • Increased caveolin-1 in intervertebral disc degeneration facilitates repairPubmed:26939667
  • Lower Serum Caveolin-1 Is Associated with Cerebral Microbleeds in Patients with Acute Ischemic StrokePubmed:27119011
  • Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive PulmonaryDisease.pubmed:27613621
  • Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis MicePubmed:29849903
  • Endothelium‐dependent hyperpolarization‐mediated vasodilatation compensates nitric oxide‐mediated endothelial dysfunction during ischemia in diabetes‐induced …Pubmed:29665152
  • The CAV1 Gene 3′ Untranslated Region Single Nucleotide Polymorphisms Are Associated with the Risk of Pulmonary Hypertension in Chinese Han Chronic …
  • SIRT6 transcriptionally regulates fatty acid transport by suppressing PPAR¦Ã34077730
  • Cav-1 Protein Levels in Serum and Infarcted Brain Correlate with Hemorrhagic Volume in a Mouse Model of Thromboembolic Stroke, Independently of Rt-PA?¡­
  • 5, 2′-Dibromo-2, 4′, 5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 ProteinPubmed:35566232

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