Monoclonal Antibody to Dihydropyrimidine Dehydrogenase (DPYD)

DPD; DHPDHase; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase

UOM
1. 20µl
2. 100µl
3. 200µl
4. 1ml
5. 10ml
FOB US$ 113.00 US$ 263.00 US$ 375.00 US$ 938.00 US$ 3,750.00
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Overview

Properties

Product No.MAC012Hu21
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsICC/IF
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only
Downloadn/a
CategoryEnzyme & Kinase Metabolic pathway

SourceMonoclonal antibody preparation, Host Mouse
Ig Isotype IgG1Kappa, Clone Number C1
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPC012Hu01-Recombinant Dihydropyrimidine Dehydrogenase (DPYD)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid, Concentration 1mg/mL

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Packages (Simulation)
Packages (Simulation)

AF488 staining on IF;
Sample: Jurkat cell
Primary Ab: 30µg/ml Mouse Anti-Human DPYD Antibody
Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu11)

ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against DPYD. It has been selected for its ability to recognize DPYD in immunohistochemical staining and western blotting.

Usage

Immunofluorescence: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Citations

The upregulation of dihydropyrimidine dehydrogenase in liver is involved in acquired resistance to 5-fluorouracilScienceDirect: S0959804912009835
The levels of urine CTX-II, C2C, and PYD in children patients with Kashin-Beck disease in Qinghai Province of ChinaPubmed: 30635000