Monoclonal Antibody to Endoglin (ENG) Rattus norvegicus (Rat) Monoclonal antibody

CD105; END; HHT1; ORW; ORW1; Osler-Rendu-Weber Syndrome 1

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number 17
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPA980Ra01-Recombinant Endoglin (ENG)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Monoclonal Antibody to Endoglin (ENG) Packages (Simulation)
  • Monoclonal Antibody to Endoglin (ENG) Packages (Simulation)
  • MAA980Ra21.jpg Figure. Western Blot; Sample: Recombinant ENG, Rat.
  • Monoclonal Antibody to Endoglin (ENG) Western Blot; Sample: Human Lung lysate
    Primary Ab: 3µg/ml Mouse Anti-Rat ENG Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19) Selected
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against ENG. It has been selected for its ability to recognize ENG in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-3µg/mL;
Immunohistochemistry: 5-30µg/mL;
Immunocytochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Homo sapiens (Human)

Giveaways

Citations

  • Endothelial Dysfunction and Nailfold Videocapillaroscopy Pattern as Predictors of Digital Ulcers in Systemic Sclerosis: a Cohort Study and Review of the LiteraturePubMed: 26142066
  • Peripheral vasculopathy in Raynaud phenomenon: Vascular disease biomarkersscience:S1646706X16300052
  • Impaired angiogenesis as a feature of digital ulcers in systemic sclerosisPubmed:26920752
  • Diagnostic and prognostic significance of serum soluble endoglin levels in preeclampsia and eclampsiapubmed:27563629
  • Relationships between serum selenium and zinc concentrations versus profibrotic and proangiogenic cytokines (FGF-19 and endoglin) in patients with alcoholic liver cirrhosis.pubmed:28954507
  • The predictive role of PlGF/sENG ratio in fetal growth restriction of early beginning associated with pre-eclampsia

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