Monoclonal Antibody to Exportin 1 (XPO1) Homo sapiens (Human) Monoclonal antibody

Exp1; CRM1 Homolog,Yeast; Chromosome region maintenance 1 protein homolog

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG, Clone Number n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Exportin 1 (XPO1) Packages (Simulation)
  • Monoclonal Antibody to Exportin 1 (XPO1) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against XPO1. It has been selected for its ability to recognize XPO1 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Inactivation of the p53–KLF4–CEBPA Axis in Acute Myeloid LeukemiaPubMed: 26408402
  • Inactivation of the p53–KLF8–CEBPA Axis in Acute Myeloid LeukemiaPubMed: 26408402
  • Mahendra Seervi, S. Sumi, Aneesh Chandrasekharan, Abhay K. Sharma &Doi: 10.1007/s13402-019-00451-1
  • Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathwayPubmed: 31147963
  • XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial InfarctionPubmed: 31768947
  • Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry34472763

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