Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) Homo sapiens (Human) Monoclonal antibody

BMP11; Bone morphogenetic protein 11

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number C4
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPC113Hu01-Recombinant Growth Differentiation Factor 11 (GDF11)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) Packages (Simulation)
  • Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) IHC Images
  • MAC113Hu21.jpg Figure. Western Blot; Sample: Recombinant GDF11, Human.
  • Monoclonal Antibody to Growth Differentiation Factor 11 (GDF11) Western Blot; Sample: Lane1: Rat Cerebrum lysate; Lane2: Rat Spinal cord lysate;
    Primary Ab: 2µg/ml Mouse Anti-Human GDF11 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19) Selected
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against GDF11. It has been selected for its ability to recognize GDF11 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Rattus norvegicus (Rat)

Giveaways

Citations

  • Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic micePubMed: 26317549
  • TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Micepubmed:27611336
  • GDF11 is increased in patients with myelodysplastic syndromefiles:ijcep0024948.pdf
  • GDF11 does not improve the palmitate induced insulin resistance in C2C12.pubmed:28485800
  • РОЛЬ ДИФФЕРЕНЦИРОВОЧНОГО ФАКТОРА РОСТА 11 (GDF11) В РЕГУЛЯЦИИ ЛИПИДНОГО ОБМЕНА И КАРДИОГЕМОДИНАМИЧЕСКИХ ФУНКЦИЙ …Cyberleninka:Source
  • GDF11 is increased in patients with aplastic anemiaPubmed: 30727851
  • GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs33764670
  • The relationship between transforming growth factor β superfamily members (GDF11 and BMP4) and lumbar spine bone mineral density in postmenopausal Chinese …34417839
  • Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and …34336096

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