Monoclonal Antibody to Neurogranin (NRGN)

Ng; NEUG; Protein Kinase C Substrate RC3

UOM
1. 20µl
2. 100µl
3. 200µl
4. 1ml
5. 10ml
FOB US$ 104.00 US$ 243.00 US$ 347.00 US$ 868.00 US$ 3,470.00
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Overview

Properties

Product No.MAA404Hu23
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsWB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only
DownloadInstruction Manual
CategoryNeuro science

SourceMonoclonal antibody preparation, Host Mouse
Ig Isotype IgG1 Kappa, Clone Number C1
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPA404Hu01-Recombinant Neurogranin (NRGN)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid, Concentration 1mg/ml

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Packages (Simulation)
Packages (Simulation)

DAB staining on IHC-P; Sample: Human Cerebrum Tissue; Primary Ab: 30µg/ml Mouse Anti-Human NRGN Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
DAB staining on IHC-P;
Sample: Human Kidney Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human NRGN Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Sample: Human Cerebrum Tissue
Primary Ab: 30µg/ml Mouse Anti-Human NRGN Antibody
Control: Used PBS instead of primary antibody
Second Ab: 2µg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Sample: Human Kidney Tissue
Primary Ab: 30µg/ml Mouse Anti-Human NRGN Antibody
Control: Used PBS instead of primary antibody
Second Ab: 2µg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)

Western Blot; Sample: Lane1: Mouse Cerebrum lysate; Lane2: Rat Cerebrum lysate Primary Ab: 2µg/mL Mouse Anti-Human NRGN Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)

ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against NRGN. It has been selected for its ability to recognize NRGN in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa; Porcine (Pig)

Giveaways

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Citations

Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profilePubmed:27408937
Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal agingPubmed:27231710
Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s diseasepubmed:27601437
Growth Hormone-Releasing Hormone Administration in Mild Cognitive Impairment and Its Impact on Neuronal Exosome Biomarkers of DementiaDoi: 10.3233/JAD-180302
SYNAPTIC PROTEIN BIOMARKERS AND DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS
The diagnostic value of neurogranin in patients with carbon monoxide poisoning: Can it show early neurological damage?34388687