Monoclonal Antibody to Neurogranin (NRGN) Homo sapiens (Human) Monoclonal antibody

Ng; NEUG; Protein Kinase C Substrate RC3

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG1 Kappa, Clone Number C12
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPA404Hu01-Recombinant Neurogranin (NRGN)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Monoclonal Antibody to Neurogranin (NRGN) Packages (Simulation)
  • Monoclonal Antibody to Neurogranin (NRGN) Packages (Simulation)
  • Monoclonal Antibody to Neurogranin (NRGN) DAB staining on IHC-P; Sample: Porcine Cerebrum Tissue Primary Ab: 40µg/ml Mouse Anti-Human NRGN Antibody Control: Used PBS instead of primary antibody Second Ab: 2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Neurogranin (NRGN) DAB staining on IHC-P;
    Sample: Porcine Kidney Tissue
    Primary Ab: 40µg/ml Mouse Anti-Human NRGN Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • MAA404Hu27.jpg Western Blot; Samples: Lane1: Porcine Cerebrum lysate; Lane2: Mouse Cerebrum lysate; Lane3: Rat Cerebrum lysate; Primary Ab: 2µg/ml Mouse Anti-Human NRGN Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against NRGN. It has been selected for its ability to recognize NRGN in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa; Porcine (Pig)

Giveaways

Citations

  • Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profilePubmed:27408937
  • Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal agingPubmed:27231710
  • Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s diseasepubmed:27601437
  • Growth Hormone-Releasing Hormone Administration in Mild Cognitive Impairment and Its Impact on Neuronal Exosome Biomarkers of DementiaDoi: 10.3233/JAD-180302
  • SYNAPTIC PROTEIN BIOMARKERS AND DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS
  • The diagnostic value of neurogranin in patients with carbon monoxide poisoning: Can it show early neurological damage?34388687

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