Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) Homo sapiens (Human) Polyclonal antibody

AXLLG; AXSF; AXL Stimulatory Factor; AXL receptor tyrosine kinase ligand

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPA204Hu02-Recombinant Growth Arrest Specific Protein 6 (GAS6)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) Packages (Simulation)
  • Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) Packages (Simulation)
  • Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) Used in DAB staining on fromalin fixed paraffin- embedded kidney tissue
  • Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) AF488 staining on IF;
    Sample: Hela cell
    Primary Ab: 20µg/ml Rabbit Anti-Human GAS6 Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb11)
  • PAA204Hu02.jpg Figure. Western Blot; Sample: Recombinant GAS6, Human.
  • Polyclonal Antibody to Growth Arrest Specific Protein 6 (GAS6) Western Blot; Sample: Rat Heart lysate;
    Primary Ab: 1µg/ml Rabbit Anti-Human GAS6 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19) Selected
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against GAS6. It has been selected for its ability to recognize GAS6 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Rattus norvegicus (Rat)

Giveaways

Citations

  • Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells.pubmed:27890915
  • The effects of Parenteral K1 administration in Pseudoxanthoma elasticum Patients Versus controls. a Pilot studyPubmed:29713628
  • DAPK and CIP2A are involved in GAS6/AXL-mediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injuryPubmed:29464081
  • Gamma-glutamyl carboxylated Gas6 mediates the beneficial effect of vitamin K on lowering hyperlipidemia via regulating the AMPK/SREBP1/PPARα signaling …Pubmed: 31226525
  • KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathwayPubmed: 33139930
  • 重度子痫前期患者血清GAS6 与其他炎症因子的相关性研究
  • Gamma-glutamyl carboxylated Gas6 facilitates the prophylactic effect of vitamin K in inhibiting hyperlipidemia-associated inflammatory pathophysiology via arresting MCP-1/ICAM-1 mediated monocyte-hepatocyte adhesion33789149

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