Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Homo sapiens (Human) Polyclonal antibody

PDF; MIC1; NAG-1; PLAB; PTGFB; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; Placental bone morphogenetic protein; Prostate differentiation factor

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPC034Hu02-Recombinant Growth Differentiation Factor 15 (GDF15)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Packages (Simulation)
  • Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Packages (Simulation)
  • Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Used in DAB staining on fromalin fixed paraffin-embedded Intestine tissue
  • PAC034Hu02.jpg Figure. Western Blot; Sample: Recombinant GDF15, Human.
  • Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Western Blot; Sample: Mouse Placenta lysate
    Primary Ab: 2μg/ml Rabbit Anti-Human GDF15 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against GDF15. It has been selected for its ability to recognize GDF15 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse)

Giveaways

Citations

  • Growth Differentiation Factor 15 and Coronary Collateral FormationPubMed: 20014173
  • Elevated levels of GDF-15 is associated with increased angiotensin II in hypertensive patients with Type 2 diabetespme-2016-0030
  • Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathwayPubmed: 32798557
  • Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort
  • Serum NT©\proBNP levels are associated with cognitive functions in hemodialysis patients33423325
  • Is GDF-15 level associated with gestational diabetes mellitus and adverse perinatal outcomes?33678319
  • Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study33880052
  • Predictive value of growth differentiation factor-15 in patients with myocardial infarction
  • High Fat, High Sugar Diet and DJOS Bariatric Surgery Influence Plasma Levels of Fetuin-B, Growth Differentiation Factor-15, and Pentraxin 3 in Diet-Induced Obese …34684637
  • Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation34675439
  • Growth Differentiation Factor 15 is Related with Left Ventricular Recovery in Patients with ST-Elevation Myocardial Infarction after Successful Reperfusion by …34584380
  • The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in ratPubmed:35029766
  • Plasma growth differentiation factor‐15 in patients with “lone” atrial fibrillationPubmed:35334497

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