Fibroblast Growth Factor 1, Acidic (FGF1)

ECGF; AFGF; ECGFA; ECGFB; FGF-Alpha; FGFA; HBGF1; ECGFB; HBGF1; Acidic Fibroblast Growth Factor; heparin-binding growth factor 1; Endothelial Cell Growth Factor, Beta

Fibroblast Growth Factor 1, Acidic (FGF1)

Heparin-binding growth factor 1  is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.

Organism species: Homo sapiens (Human)

Organism species: Mus musculus (Mouse)

Organism species: Rattus norvegicus (Rat)

Organism species: Sus scrofa; Porcine (Pig)

Organism species: Bos taurus; Bovine (Cattle)

Organism species: Capra hircus; Caprine (Goat)

Organism species: Ovis aries; Ovine (Sheep)

Organism species: Chicken (Gallus)