Programmed Cell Death Protein 1 Ligand 1 (PDL1)
CD274; PDCD1LG1; B7-H; B7H1; PD-L1; PDCD1L1; PDCD1-LG1; Programed Death Ligand 1
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CD274 (Cluster of Differentiation 274) also known as PD-L1 (Programed Death Ligand-1) or B7-H1 is a protein,PD-L1 binds to its receptor, PD-1, found on activated T cells, B cells, and myeloid cells, to modulate activation or inhibition. The affinity between PD-L1 and PD-1, as defined by the dissociation constant Kd, is 770nM. Interestingly, PD-L1 also has an appreciable affinity for the costimulatory molecule CD80 (B7-1), but not CD86 (B7-2).
CD80's affinity for PD-L1, 1.4µM, is intermediate between its affinities for CD28 and CTLA-4 (4.0µM and 400nM, respectively). The related molecule PD-L2 has no such affinity for CD80 or CD86, but shares PD-1 as a receptor (with a stronger Kd of 140nM).
Organism species: Homo sapiens (Human)
- Recombinant protein RPA788Hu01 Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Eukaryotic protein EPA788Hu61 Eukaryotic Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Active protein APA788Hu61 Active Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Recombinant protein RPA788Hu02 Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Polyclonal antibody PAA788Hu01 Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu22 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Labelled antibody LAA788Hu72 Biotin-Linked Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu21 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu23 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu24 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu25 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu27 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu29 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu26 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Hu28 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Sandwich ELISA SEA788Hu ELISA Kit for Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Sandwich CLIA SCA788Hu CLIA Kit for Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA788Mu01 Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Recombinant protein RPA788Mu02 Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Polyclonal antibody PAA788Mu01 Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Polyclonal antibody PAA788Mu02 Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Sandwich ELISA SEA788Mu ELISA Kit for Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Antibody ELISA AEA788Mu ELISA Kit for Anti-Programmed Cell Death Protein 1 Ligand 1 Antibody (Anti-PDL1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA788Ra01 Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Polyclonal antibody PAA788Ra01 Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Ra21 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Ra22 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Ra23 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Monoclonal antibody MAA788Ra24 Monoclonal Antibody to Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock
- Sandwich ELISA SEA788Ra ELISA Kit for Programmed Cell Death Protein 1 Ligand 1 (PDL1) In Stock