Polyclonal Antibody to Glutamine synthetase (GS)

GLNS; GLUL; Glutamate-Ammonia Ligase; Glutamate decarboxylase

UOM
1. 20µl
2. 100µl
3. 200µl
4. 1ml
5. 10ml
FOB US$ 105.00 US$ 245.00 US$ 350.00 US$ 875.00 US$ 3,500.00
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Overview

Properties

Product No.PAD761Hu01
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsWB; IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only
DownloadInstruction Manual
CategoryEnzyme & Kinase

SourcePolyclonal antibody preparation, Host Rabbit
Ig Type IgG, Potency n/a
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
LabelNone
Immunogen RPD761Hu01-Recombinant Glutamine synthetase (GS)
Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
TraitsLiquid, Concentration 0.2mg/mL

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Packages (Simulation)
Packages (Simulation)

DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 20μg/ml Rabbit Anti-Human GS Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Human Cerebellum Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Human GS Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)

Western Blot; Sample: Porcine Cerebrum lysate Primary Ab: 0.5µg/ml Rabbit Anti-Human GS Antibody Second Ab: 0.2µg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)

ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against GS. It has been selected for its ability to recognize GS in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
mmunohistochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Sus scrofa; Porcine (Pig)

Giveaways

Increment services

Citations

Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s diseasepubmed:27511944
High complement levels in astrocyte‐derived exosomes of Alzheimer diseasePubmed:29406582
Sex differences in the glutamate signaling pathway in juvenile ratsPubmed:28861894
Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer diseasePubmed:29924942
Glutamine synthetase promotes tumor invasion in hepatocellular carcinoma through mediating epithelial–mesenchymal transitionPubmed: 31652385
Traumatic brain injury increases plasma astrocyte‐derived exosome levels of neurotoxic complement proteinsPubmed: 31916313
Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosisPubmed: 33106473
Drug Repurposing of Asparaginase and Vitamin C Targeting Glutamine Synthetase Improves Anticancer Effect in Metastatic Castration-resistant Prostate …