Monoclonal Antibody to Urocortin 2 (UCN2) Homo sapiens (Human) Monoclonal antibody

URP; SRP; UCN-II; UCNII; Stresscopin-Related Peptide; Urocortin-related peptide

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG, Clone Number C11
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Urocortin 2 (UCN2) Packages (Simulation)
  • Monoclonal Antibody to Urocortin 2 (UCN2) Packages (Simulation)
  • Monoclonal Antibody to Urocortin 2 (UCN2) AF488 staining on IF;
    Sample: U2OS cell
    Primary Ab: 20µg/ml Mouse Anti-Human UCN2 Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu11)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against UCN2. It has been selected for its ability to recognize UCN2 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • High-Sensitivity Sandwich ELISA for Plasma NT-proUcn2: Plasma Concentrations and Relationship to Mortality in Heart Failure.Pubmed:27127183
  • Urocortins: Actions in health and heart failurepubmed:28887029
  • Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertensionPubmed:29584808
  • Glucocorticoid withdrawal affects stress‐induced changes in urocortin 2 gene expression in the rat adrenal medulla and brainPubmed:29604138
  • Evaluation of Serum Urocortin 2 Levels in Patients with HypertensionPubmed: 31925709
  • Urocortin-2 in acute heart failure: role as a marker of volume overload and pulmonary hypertension33994037

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