Canine Model for Laryngeal Paralysis (LP)

UOM
1. Each case
FOB US$
Quantity

No quotes Distributors

Overview

Properties

Product No.DSI660Ca01
Organism SpeciesCanis familiaris; Canine (Dog) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applicationsn/a
Research use only
Downloadn/a
CategoryEye, ear, nose, throat and oral systems

Prototype SpeciesHuman
SourceInduced by operation
Model Animal StrainsClosed group, general level, age 6 to 9 months old, weight: 6-10kg.
Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
Modeling Period4-6 weeks

Share your citation Upload your experimental result Review Leave a message

Sign into your account

Email *

Password *

Verification code*

Create a new account

Share a new citation as an author

Title *

Journal

Link*

Upload your experimental result

Application*

Experimental result*

Review

Rating

Serial No* Please attach serial No. on instruction manual

Contact us
Please fill in the blank.

Name*

Organization

Address

E-mail address*

Telephone

Inquiry*

Verification code* CheckCode

Packages (Simulation)
Packages (Simulation)

ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Choose experimental dogs, according to the dose of 30 ~ 50 mg/kg body weight by intramuscular injection of ketamine hydrochloride anesthesia, animals after general anesthesia, to fix its lie on your back neck midline incision, skin incision, along the strip muscle midline anterior portion, expose thyroid cartilage, cricoid cartilage and trachea, found in tracheoesophageal groove on one side of the laryngeal recurrent nerve, confirmed by electrical stimulation of the laryngeal recurrent nerve after cut off 1 cm, ligation, on both ends on laryngeal nerve ligation on both ends, the unilateral laryngeal paralysis animal model. For animal models of bilateral laryngeal paralysis, the same method can be used to cut off the other side of the laryngeal recurrent nerve.

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.