Cavia Model for Chronic Obstructive Pulmonary Disease (COPD) Cavia (Guinea pig ) Disease model

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Overview
Properties
  • Prototype SpeciesHuman
  • Sourceinduced by smoking
  • Model Animal StrainsGuinea pig, healthy, male and female, body weight 350g~700g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
  • Modeling Period4-6 weeks
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  • Cavia Model for Chronic Obstructive Pulmonary Disease (COPD) Packages (Simulation)
  • Cavia Model for Chronic Obstructive Pulmonary Disease (COPD) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Modeling Method

Model evaluation

Pathological results

Cytokines level

Statistical analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison , P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

Citations

  • Overexpression of histone deacetylase SIRT1 exerts an anti-angiogenic role in diabetic retinopathy via miR-20a elevation and YAP/HIF1α/VEGFA depletionPubmed: 32776826
  • Circular RNA circBbs9 promotes PM2. 5-induced lung inflammation in mice via NLRP3 inflammasome activationPubmed: 32707273

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